Researcher
Sabine Tejpar
- Disciplines:Oncology
Affiliations
- Digestive Oncology (Division)
Responsible
From1 Aug 2022 → Today - Digestive Oncology (Division)
Member
From1 Aug 2022 → Today - Molecular Digestive Oncology (Division)
Member
From1 Jan 2012 → 31 Jul 2022 - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2003 → 31 Dec 2011
Projects
11 - 20 of 56
- Using mucins as friends in colorectal cancer diagnostics and treatmentFrom20 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling the epigenetic mechanisms behind epithelial cell plasticity in metaplastic colorectal cancerFrom19 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Disentangling the CD4-DC-CD8 functionalities and interactions to treat colorectal tumoursFrom1 Sep 2022 → 13 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- HIstopathology-based predictions by Multi-modal data Integration for COlorectal cancer diagnosticsFrom15 Jun 2022 → TodayFunding: BOF - various
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Personalized multimodal treatment for resectable esophageal cancer by detecting minimal residual disease (MRD) using circulating tumor DNA (ctDNA):From11 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Characterizing the development and heterogeneity in the colorectal tumor ecosystemFrom12 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Artificial Intelligence/Machine Learning (AI/ML) -driven dissection of the microbiome’s multi-factorial impact on colorectal cancer (CRC) immune-landscape to guide clinical immunotherapy.From1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- Comprehensive functional characterization of the immune response to colorectal cancerFrom1 Oct 2021 → TodayFunding: BOF - ZAP BOF mandates
Publications
1 - 10 of 250
- Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines.(2024)
Authors: Pavlo Lutsik, Sabine Tejpar
Pages: 109247 - CD4+ T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy.(2024)
Authors: Amelie Franken, Michel Bila, Aurelie Mechels, Jeroen Van Dessel, Bram Boeckx, Sigrid Hatse, Esther Hauben, Vincent Vander Poorten, Katy Vandereyken, Sabine Tejpar, et al.
Pages: 541 - 558.e7 - Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology.(2024)
Authors: Tatjana Jatsenko, Stefania Tuveri, Lore Lannoo, Kristel Van Calsteren, Liesbeth Lenaerts, Sabine Tejpar, Bernard Thienpont, Joris Vermeesch
Pages: 2220 - Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer(2024)
Authors: Sabine Tejpar
- Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer(2024)
Authors: Sara Verbandt, An Coosemans, Sabine Tejpar
- Lymph node and tumor-associated PD-L1+macrophages antagonize dendritic cell vaccines by suppressing CD8+T cells(2024)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Sabine Tejpar, Steven De Vleeschouwer, Abhishek Garg
- Neoantigen identification: Technological advances and challenges.(2024)
Authors: Ting Pu, Sabine Tejpar, Sara Verbandt
Pages: 265 - 302 - Trial watch: chemotherapy-induced immunogenic cell death in oncology(2023)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Lisa Kinget, An Coosemans, Steven De Vleeschouwer, Els Wauters, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, et al.
- Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and ATM, a Belgian Precision tumor-agnostic phase II study(2023)
Authors: Sabine Tejpar
- Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer(2023)
Authors: Sara Verbandt, Isaure Vanmeerbeek, Jenny Sprooten, Gert De Hertogh, Xavier Sagaert, Albert Wolthuis, Stefan Naulaerts, Sabine Tejpar, Abhishek Garg
Patents
1 - 1 of 1
- Colon cancer (Inventor)