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Researcher
Rita Derua
- Disciplines:Posttranslational modifications, Interactomics, Proteomics, Spectrometry
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 11
- Ultra-sensitive minimal residual disease assessment by blood-based clonotypic mass spectrometry approach in plasma cell dyscrasias (MASSIAS)From1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Targeted mass spectrometry-based quantification of autoantibodies in systemic rheumatic diseasesFrom1 Oct 2021 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Development and clinical validation of a multiplexed massspectrometry- based assay to improve diagnosis of Rheumatoid ArthritisFrom1 Jan 2021 → 31 Dec 2022Funding: FWO Applied Biomedical Research (TBM)
- Mass spectrometry-based autoantibody tests for specific diagnosis of autoimmune diseasesFrom1 Oct 2020 → 30 Sep 2022Funding: IOF - technology validation in lab
- Translational research related to Corona-Covid 19From1 Apr 2020 → 31 Mar 2021Funding: IOF - technology validation in lab, BOF - various
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting radiotherapy resistance in Head and Neck Cancers: the potential biomarker role of TIPRL1 and CIP2A, two cellular inhibitors of Protein Phosphatase 2AFrom1 Jan 2018 → 22 Nov 2023Funding: BOF - doctoral mandates
- Targeting radiation resistance of Head and Neck Squamous Cell CarcinomaFrom1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- The role of the Protein Phosphatase 2A Activator PTPA in KRAS-mutant non-small-cell lung cancer development and treatment resistanceFrom1 Feb 2015 → 10 Nov 2021Funding: BOF - Doctoral projects
- Novel insights in the pharmacological inhibition and isoform-specific regulation of protein kinase D2.From1 Mar 2013 → 5 Jul 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 94
- Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease(2022)
Authors: Rita Derua
- FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4(2022)
Authors: Etienne Waelkens, Rita Derua, Johan Swinnen, Jonas Dehairs
- Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells(2022)
Authors: Celien Lismont, Iulia Revenco, Mohamed Hussein, Paul P Van Veldhoven, Rita Derua, Marc Fransen
- Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting(2022)
Authors: Nicole Rufo, Rita Derua, Abhishek Garg, Michael Dewaele, Peter de Witte, Steven Verhelst, Patrizia Agostinis
Pages: 230 - 245 - The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes(2021)
Authors: Rita Derua, Johan Swinnen
- De rol van de Proteïne Fosfatase 2A Activator PTPA in KRAS-mutante niet-kleincellige longkankerontwikkeling en behandelingsresistentie(2021)
Authors: Bob Meeusen, Veerle Janssens, Johan Van Lint, Rita Derua
- Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition(2021)
Authors: Xander Spotbeen, Jonas Dehairs, Rita Derua, Etienne Waelkens, Johan Swinnen
Pages: 4981 - 4993 - Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution.(2021)
Authors: Lieven Thorrez, Etienne Waelkens, Rita Derua, Johan Buyse, Frans Schuit
- Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease(2021)
Authors: Iris Verbinnen, Pieter Vaneynde, Rita Derua, Veerle Janssens
Pages: 1 - 22 - Effect of Graphene and Graphene Oxide on Airway Barrier and Differential Phosphorylation of Proteins in Tight and Adherens Junction Pathways(2021)
Authors: Jeroen Vanoirbeek, Rita Derua, Peter Hoet, Manosij Ghosh