Researcher
Remy Loris
- Research Expertise
(Vrije Universiteit Brussel):
- Protein crystallography
- Biophysics
- Bio-SAXS (Small angle X-ray diffraction on biological molecules)
- Structural biology
- Persistence
- Bacterial stress response
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology
- Disciplines (Flanders Institute for Biotechnology):(Bio)molecular modelling and design, Analytical biochemistry, Medical biophysics
- Disciplines (Vrije Universiteit Brussel):Infectious diseases, Molecular biophysics, Proteins, Structural biology
- Users of research expertise
(Vrije Universiteit Brussel):
- Protein crystallography
- Biophysics
- Bio-SAXS (Small angle X-ray diffraction on biological molecules)
- Structural biology
- Persistence
- Bacterial stress response
Affiliations
- Structural Biology Brussels (Research group)
Member
From1 Jan 1991 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2023 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2023 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Apr 2020 → 31 Dec 2022 - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Loris Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 May 2012 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2008 → 20 Oct 2022 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2003 → 30 Apr 2012 - Ultrastructure (Research group)
Member
From1 Jan 1991 → 31 Dec 2010 - Department of General Biology (Research group)
Member
From1 Oct 1990 → 30 Sep 1992 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 1990 → 30 Sep 2003
Projects
1 - 10 of 20
- Uncovering the effect of long non-coding RNAs on liquid-liquid phase separation of androgen receptor in prostate cancerFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Molecular basis of DNA recognition by SOG1: the master regulator for DNA damage control in plantsFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Nanobodies to recognize non-canonical DNA structures and regulate their formation in vivoFrom1 Oct 2021 → TodayFunding: BOF - mobility
- Structural and thermodynamic dissection of fuzzy protein-DNA interactions in a prokaryotic transcription factorFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Functional-structural analysis of Casein Kinase 2 and SOG1 in response to Al-induced DNA damage and phosphate starvationFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Mechanism of Gyrase-poisoning by ParE and its rejuvenation by ParDFrom1 Nov 2019 → 31 Jan 2024Funding: FWO fellowships
- Regulation of persistence by the paaAR-paaA2-parE2 and cog4197-duf1019 operons from E. coli O157From1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- SOGI as a target for chemical inhibition to promote aluminum tolerance in barley and cornFrom1 Jan 2016 → 31 Dec 2019Funding: FWO fellowships
- Regulatory mechanisms in bacterial toxin-antitoxin modulesFrom1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Structure-function analysis of a novel plant-specific inhibitor of the anaphase-promoting complexFrom1 Oct 2013 → 30 Sep 2017Funding: FWO fellowships
Publications
41 - 50 of 56
- Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF(2016)
Authors: Valentina Zorzini, Andrej Mernik, Yann Sterckx, Natalie De Jonge, Abel Garcia-Pino, Henri De Greve, Wim Versées, Remy Loris
Pages: 10950-10956 - A unique hetero-hexadecameric architecture displayed by the E. coli O157 PaaA2-ParE2 antitoxin-toxin complex(2016)
Authors: Yann Sterckx, Thomas Jove, Aliaksandr Shkumatau, Abel Garcia-Pino, Lieselotte Geerts, Maia De Kerpel, Jurij Lah, Henri De Greve, Laurence Van Melderen, Remy Loris
Pages: 1589-1603 - An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation(2016)
Authors: Abel Garcia-Pino, Steven De Gieter, Ariel Talavera Perez, Henri De Greve, Ruslan Efremov, Remy Loris
Pages: 490-496 - Frizzled 7 and PIP2 binding by syntenin PDZ2 domain controls Frizzled 7 trafficking and signaling.(2016)
Authors: Antonio Egea-Jimenez, Rodrigo Gallardo, Abel Garcia-Pino, Ylva Ivarsson, Anna Maria Wawrzyniak, Rudra Kashyap, Remy Loris, Joost Schymkowitz, Frederic Rousseau, Pascale Zimmermann
- Structural mimicry of receptor interaction by antagonistic IL-6 antibodies(2016)
Authors: Christophe Blanchetot, Natalie De Jonge, Aline Desmyter, Nico Ongenae, Erik Hofman, Alex Klarenbeek, Ava sadi, Anna Hultberg, Anke Kretz-Rommel, Silvia Spinelli, et al.
Pages: 13846-13854 - Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding(2015)
Authors: Valentina Zorzini, Lieven Buts, Evelyne Schrank, Yann Sterckx, Michal Respondek, Hanna Engelberg-Kulka, Remy Loris, Klaus Zangger, Nico Van Nuland
Pages: 1241-1256 - Crystallization of two operator complexes from the Vibrio cholerae higBA2 toxin-antitoxin module(2015)
Authors: San Hadzi, Abel Garcia-Pino, Kenn Gerdes, Jurij Lah, Remy Loris
Pages: 226-233 - An efficient method for the purification of proteins from four distinct toxin–antitoxin modules(2015)
Authors: Yann Sterckx, Steven De Gieter, Valentina Zorzini, San Hadzi, Sarah Haesaerts, Remy Loris, Abel Garcia-Pino
Pages: 30-40 - SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization(2014)
Authors: Marcus Fislage, Elke Brosens, Egon Deyaert, Alessandro Spilotros, E Pardon, Remy Loris, J Steyaert, Abel Garcia-Pino, Wim Versées
Pages: 5978-5992 - A nanobody modulates the p53 transcriptional program without perturbing its functional architecture(2014)
Authors: Jonas Bethuyne, Steven De Gieter, Olivier Zwaenepoel, Abel Garcia-Pino, Kaat Durinck, Adriaan Verhelle, Gholamreza Hassanzadeh Ghassabeh, Frank Speleman, Remy Loris, Jan Gettemans
Pages: 12928-12938