Researcher
Raf Sciot
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Optical genome mapping for comprehensive genetic analysis of sarcomas in a diagnostic setting.From1 Jan 2023 → TodayFunding: FWO Humanitarian research project Stand up against Cancer
- Whole-genome optical mapping for comprehensive analysis of sarcoma genomes in a diagnostic settingFrom13 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Direct detection and identification of neuro-oncology markers in brain tumoursFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Determination of genetic and therapeutic dependencies of patient-derived models of brain cancerFrom1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption
- Establishment of new research models and in vivo efficacy testing of novel treatment strategies for resistant gastrointestinal stromal tumorsFrom1 Aug 2014 → 19 May 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Human soft tissue sarcomas xenograft mouse models as an opportunity to improve the therapeutic options for patients.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Identification of novel protein kinase targets for the improvement of gastrointestinal stromal tumor (GIST) therapy: a paradigm for the optimisation of kinase targeted therapies.From1 Jan 2011 → 31 Dec 2016Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Neuropathological and functional characterization of the therapeutic effect of parkin in animal models of Parkinson's disease.From25 Aug 2009 → 7 Feb 2014Funding: FWO fellowships
Publications
21 - 30 of 261
- Plocabulin, a Novel Tubulin Inhibitor, Has Potent Antitumour Activity in Patient-Derived Xenograft Models of Soft Tissue Sarcoma(2022)
Authors: Agnieszka Wozniak, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski
- Exploring stem cell biology in pituitary tumors and derived organoids(2022)
Authors: Charlotte Nys, Ellen De Pauw, Raf Sciot, Steven De Vleeschouwer, Johan van Loon, Hugo Vankelecom
Pages: 427 - 450 - Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma(2022)
Authors: Britt Van Renterghem, Agnieszka Wozniak, Raf Sciot, Patrick Schöffski
- Anti-tumor effects of the novel KIT mutant inhibitor M4205 in patient-derived gastrointestinal stromal tumor (GIST) xenograft models(2022)
Authors: Luna De Sutter, Agnieszka Wozniak, Lore De Cock, Raf Sciot
- SPATIAL MAPPING OF THE TUMOR MICRO-ENVIRONMENT IN PEDIATRIC GLIOMA(2022)
Authors: Julie Messiaen, Yannick Van Herck, Francesca Bosisio, Isabelle Vanden Bempt, Raf Sciot, Frederik De Smet
Pages: 74 - 74 - Medial cutaneous nerve neuroma-in-continuity within the ulnar nerve: a report of 2 cases(2022)
Authors: Raf Sciot, Ilse Degreef
Pages: 521 - 526 - Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 "CREATE" Trial(2022)
Authors: Elodie Modave, Bram Boeckx, Maria Debiec-Rychter, Raf Sciot, Diether Lambrechts, Agnieszka Wozniak, Patrick Schöffski
- Enhanced Antitumor Efficacy of PhAc-ALGP-Dox, an Enzyme-Activated Doxorubicin Prodrug, in a Panel of THOP1-Expressing Patient-Derived Xenografts of Soft Tissue Sarcoma(2022)
Authors: Britt Van Renterghem, Agnieszka Wozniak, Raf Sciot, Patrick Schöffski
- Towards real-time intraoperative tissue interrogation for REIMS-guided glioma surgery(2022)
Authors: Laura Van Hese, Steven De Vleeschouwer, Tom Theys, Lien Solie, Raf Sciot, Steffen Rex, Eva Cuypers
Pages: 80 - 89 - ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition(2022)
Authors: Raf Sciot
Pages: 256 - 280