Researcher
Pieter Mestdagh
- Keywords:oncology, transcriptomics, RNA, non-coding RNA
- Disciplines:Analysis of next-generation sequence data, Cancer diagnosis, Cancer therapy, Molecular diagnostics, Development of bioinformatics software, tools and databases, Computational transcriptomics and epigenomics, Bioinformatics of disease, Bioinformatics data integration and network biology, Cancer biology, Transcription and translation, Epigenetics, Genome structure and regulation, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2006 → 30 Sep 2018
Projects
1 - 10 of 38
- Plasma cfRNA biomarker tail genes for cancer screening and monitoringFrom15 Oct 2023 → TodayFunding: IOF - technology concept exploration
- Increasing the value proposition of the IOF programs CRISParray and Amalus: CRISPRi-based target deconvolution of fibroblast modulatorsFrom15 Jul 2023 → TodayFunding: IOF - technology validation in lab
- Integration of molecular and cellular phenotypes: Optimizing complementarity of RNA-Seq and High Content Microscopy for the CRISParray platformFrom1 May 2023 → TodayFunding: IOF - technology concept exploration
- A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN)From1 Jan 2023 → TodayFunding: BOF - iBOF
- Identifying lncRNA modulators of T-cell activation to enhance immune-checkpoint inhibition therapyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Long non-coding RNA modulators of tumor immune evasionFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Incucyte S3: Comprehensive cellular phenotyping using high-throughput live cell imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Functional study of a novel, long non-coding RNA (lncRNA) upstream of ABCA4 in retina and blindnessFrom1 Nov 2022 → TodayFunding: BOF - doctoral mandates
- Mapping and disrupting molecular interactions with the long non-coding RNA NESPR in neuroblastomaFrom1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- CRISParray : accelerating drug discovery through comprehensive cellular and molecular phenotypingFrom1 Aug 2022 → TodayFunding: IWT / VLAIO personal funding - innovation mandates
Publications
11 - 20 of 261
- RNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer(2022)
Authors: Eva Hulstaert, Keren Levanon, Stefan Van Aelst, Anthony-Alexander Christidis, Ruben Zamar, Kimberly Verniers, Keren Bahar-Shany, Stav Sapoznik, Pieter Mestdagh
Pages: 155 - 164 - Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for SARS-CoV-2 RT-qPCR screening purposes(2022)
Authors: Jasper Verwilt, Jan Hellemans, Tom Sante, Pieter Mestdagh, Jo Vandesompele
- CiLiQuant : quantification of RNA junction reads based on their circular or linear transcript origin(2022)
Authors: Eva Hulstaert, Marieke Vromman, Pieter Mestdagh
- Unlocking the secrets of long non-coding RNAs in asthma(2022)
Authors: Fien Gysens, Pieter Mestdagh, Eric de Bony de Lavergne, Tania Maes
Pages: 514 - 522 - Orthogonal proteomics methods to unravel the HOTAIR interactome(2022)
Authors: Louis Delhaye, Edith De Bruycker, Pieter-Jan Volders, Daria Fijalkowska, Delphine De Sutter, Sven Degroeve, Lennart Martens, Pieter Mestdagh, Sven Eyckerman
- IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients(2022)
Authors: Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Pieter Mestdagh
- Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane(2022)
Authors: Gaëlle Houthaeve, Gerardo García-Díaz Barriga, Stephan Stremersch, Herlinde De Keersmaecker, Juan Fraire, Pieter Mestdagh, Kevin Braeckmans, Winnok De Vos
- Custom long non-coding RNA capture enhances detection sensitivity in different human sample types(2021)
Authors: Justine Nuytens, Eva Hulstaert, Pieter Mestdagh
Pages: 215 - 222 - Candidate RNA biomarkers in biofluids for early diagnosis of ovarian cancer : a systematic review(2021)
Authors: Eva Hulstaert, Keren Levanon, Pieter Mestdagh
Pages: 633 - 642 - Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2021)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1
Patents
1 - 9 of 9
- Inhibition of a lncRNA for treatment of neuroblastoma (Inventor)
- Inhibition of a lncRNA for treatment of melanoma (Inventor)
- Combinations of therapeutic agents for treating uveal melanoma (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Inhibition of a lncRNA for treatment of neuroblastoma (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Inhibition of a lncRNA for treatment of melanoma (Inventor)