Researcher
Pieter Annaert
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Department of Pharmaceutical and Pharmacological Sciences (Department)
Responsible
From1 Aug 2020 → Today - Drug Delivery and Disposition (Division)
Member
From1 Oct 2005 → Today
Projects
21 - 30 of 33
- Fixed dose combinations of an Organic Anion Transporter Polypeptide activator with a statin drug to reduce statin induced myopathyFrom3 Oct 2016 → 30 Sep 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- ANTIBACTERIAL DOSING IN SPECIAL PATIENT POPULATIONS WITH SEVERE BACTERIAL INFECTIONS: A PATIENT-ORIENTED AND COVARIATE-DRIVEN APPROACHFrom1 Oct 2016 → 30 Sep 2021Funding: BOF - Doctoral projects, BOF - doctoral mandates
- Predicting hepatic exposure to drugs based on quantitative insight into underlying disposition mechanismsFrom1 Jan 2016 → 31 Jan 2020Funding: Baekeland
- Drug-induced cholestasis: in vitro detection and mechanistic insights.From1 Jan 2016 → 5 Jun 2020Funding: FWO Strategic Basic Research Grant
- Selective modulation of hepatic transport proteins.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Formation of endothelial networks in human tissue-engineered skeletal muscleFrom1 Oct 2014 → 23 May 2019Funding: BOF - Doctoral projects
- Understanding Drug-Induced Cholestasis: Mechanistic exploration of hepatic bile acid dispositionFrom1 Feb 2013 → 20 Sep 2017Funding: BOF - Doctoral projects
- Transplacental passage of paracetamol and its metabolitesFrom1 Oct 2012 → 26 Sep 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development, validation and application of complementary in vitro models for the prediction of in vivo clearance of drug candidates in specific populations.From1 Oct 2011 → 18 Feb 2016Funding: IWT personal funding - strategic basic research grants
- Development and integrated use of novel preclinical models to assess intestinal absorption and hepatic elimination in order to achieve accelerated biopharmaceutical drug profiling.From1 Oct 2009 → 5 Oct 2014Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 253
- Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol - A contribution from the ConcePTION project(2024)
Authors: Martje Van Neste, Nina Nauwelaerts, Michael Ceulemans, Kristel Van Calsteren, An Eerdekens, Pieter Annaert, Karel Allegaert, Anne Smits
- Second generation Al18F-labeled D-amino acid peptide for CXCR4 targeted molecular imaging.(2024)
Authors: Tom Van Loy, Christophe Deroose, Michel Koole, Dominique Schols, Kristof De Vos, Pieter Annaert, Frederik Cleeren
Pages: 108906 - Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on "De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling"(2024)
Authors: Karel Allegaert, Anne Smits, Pieter Annaert
- A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia(2023)
Authors: Pieter Annaert, Djalila Mekahli, Anne Smits, Karel Allegaert
- Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds(2023)
Authors: Kristof De Vos, Teresa Izuel Idoype, Pieter Annaert, Frederic Lluis Vinas, Catherine Verfaillie
Pages: 1076 - 1088 - Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants—A Contribution from the ConcePTION Project(2023)
Authors: Martje Van Neste, Annick Bogaerts, Nina Nauwelaerts, Anne Smits, Pieter Annaert, Karel Allegaert
- PBPK Modelling for Drugs Cleared by Non-CYP Enzymes: State-of-the-Art and Future Perspectives.(2023)
Authors: Karen Leys, Pieter Annaert
Pages: DMD-AR-202 - Role of connexin and pannexin signaling in cholestasis(2023)
Authors: Axelle Cooreman, Pieter Annaert
- Assessment of in vitro antimicrobial activity of clindamycin metabolites against Staphylococcus species(2023)
Authors: Greet Van De Sijpe, Karel Allegaert, Jef Rozenski, Pieter Annaert, Stefanie Desmet
Pages: 1345 - 1347 - Assessment of in vitro antimicrobial activity of clindamycin metabolites against Staphylococcus species(2023)
Authors: Greet Van De Sijpe, Laura Armengol Álvarez, Agustos Cetin Ozbey, Karel Allegaert, Jef Rozenski, Pieter Annaert, Stefanie Desmet, Isabel Spriet
Pages: 1345 - 1347