Researcher
Paul Proost
- Disciplines:Autoimmunity, Inflammation, Innate immunity, Transplantation immunology, Cell movement, Proteins
Affiliations
- Molecular Immunology (Rega Institute) (Lab)
Responsible
From1 Jan 2019 → Today - Immunity and Inflammation Research Group (Division)
Responsible
From1 Jan 2019 → Today - Molecular Immunology (Rega Institute) (Lab)
Member
From1 Oct 2003 → Today - Department of Microbiology, Immunology and Transplantation (Department)
Member
From1 Oct 1999 → 30 Sep 2006
Projects
21 - 30 of 47
- Development of the first experimental model for Ilhéus vírus (ILHV) infection in mice and investigation of therapeutic strategies.From23 Sep 2019 → 23 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Different approaches to understand the role of chemokines in murine models of lung inflammationFrom4 Jun 2019 → 13 Dec 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- A blueprint of citrullination in inflammationFrom1 Jan 2019 → 21 Dec 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Characterization and therapeutic potential of chemokine action in sepsis and flavivirus-induced encephalitisFrom1 Jan 2019 → 31 Dec 2021Funding: International Cooperation and Mobility
- Immunome project consortium for AutoInflammatory DisordersFrom1 May 2018 → TodayFunding: H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture, marine and maritime research and the bio-economy
- Neutrophil migration and activation in auto-inflammatory diseases: role of the chemokine network and of posttranslational modification of chemokinesFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Inhibition of inflammation induced by ischemia-reperfusion injuryFrom1 Oct 2017 → 30 Nov 2022Funding: FWO Strategic Basic Research Grant
- The significance of chemokine-glycosaminoglycan interactions in cancer progressionFrom1 Oct 2017 → 17 Nov 2022Funding: FWO fellowships
- Functional subset definition and molecular regulation of neutrophils and natural killer cells in infection and inflammation.From1 Oct 2017 → 30 Sep 2023Funding: BOF - projects, Fund Recuperation Fiscal Exemption
- Biochemical and functional study of post-translationally modified CXC chemokines in the tumor microenvironmentFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 214
- Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.(2024)
Authors: Simon Feys, Sam Vanmassenhove, Bram Boeckx, Seppe Cambier, Yves Debaveye, Greet Hermans, Katrien Lagrou, Johan Neyts, Marijke Peetermans, Joana Duarte Da Rocha Pereira, et al.
Pages: e247 - e260 - Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity(2024)
Authors: Sam Noppen, Mieke Gouwy, Lisa Verhallen, Mirre De Bondt, Dominique Schols, Pedro Elias Marques, Sofie Struyf, Paul Proost
- Biallelic mutations in the CFHR genes underlying atypical hemolytic uremic syndrome in a patient with catastrophic adult-onset Still's disease and recurrent macrophage activation syndrome: A case report(2023)
Authors: Luna Dillemans, Youri Bekhuis, Lien De Somer, Patrick Matthys, Jeroen Breckpot, Thomas Tousseyn, Marijke Peetermans, Paul Proost, Carine Wouters, Steven Vanderschueren
- Frequent Allergic Sensitization to Farmed Edible Insects in Exposed Employees(2023)
Authors: Janne Goossens, Anne-Charlotte Jonckheere, Mieke Gouwy, Steven Ronsmans, Sofie Vandenbroeck, Lieven Dupont, Jeroen Vanoirbeek, Dominique Bullens, Christine Breynaert, Paul Proost, et al.
Pages: 3732 - + - Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5(2023)
Authors: Sara Schuermans, Paul Proost
Pages: 3049 - 3060 - A stabilized CXCL9(74-103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate(2023)
Authors: Alexandra De Zutter, Luna Dillemans, Sam Noppen, Helena Crijns, Paulien Verscheure, Janne Verhaegen, Dominique Schols, Paul Proost, Sofie Struyf
Pages: 2808 - 2822 - Characterization of neutrophils and chemokine proteolysis in COVID-19 and lung transplantation(2023)
Authors: Seppe Cambier, Paul Proost, Robin Vos, Bart Vanaudenaerde
- Endotyping of IgE-Mediated Polyethylene Glycol and/or Polysorbate 80 Allergy(2023)
Authors: Toon Ieven, Paul Proost, Glynis Frans, Christine Breynaert, Dominique Bullens, Rik Schrijvers
Pages: 3146 - 3160 - Fast and furious: The neutrophil and its armamentarium in health and disease(2023)
Authors: Mieke Gouwy, Lien De Somer, Ghislain Opdenakker, Paul Proost
Pages: 1537 - 1606 - Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients.(2023)
Authors: Seppe Cambier, Fabio Beretta, Ana Carolina De Carvalho, Janne Kaes, Pierre Van Mol, Els Wauters, Greet Hermans, Bart Vanaudenaerde, Robin Vos, Joost Wauters, et al.