Researcher
Paul Declerck
- Disciplines:Laboratory medicine, Regenerative medicine, Other basic sciences, Other health sciences, Other medical and health sciences, Medical biotechnology, Drug discovery and development, Pharmaceutics
Affiliations
- Therapeutic and Diagnostic Antibodies (Division)
Member
From1 Apr 2013 → 30 Sep 2023
Projects
1 - 10 of 28
- An integrated platform for the identification, isolation and characterization of human clock antibodies.From1 Jul 2021 → TodayFunding: Department Coordination
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- A Pharmacometrics Approach to Improve Dose Individualisation Methods of Biologicals in Patients with Chronic Inflammatory DiseasesFrom13 Oct 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Development and streamlining a validation and implementation workflow for model-informed precision dosing for biologicals and antimicrobialsFrom1 Oct 2020 → 30 Sep 2022Funding: IOF - technology validation in lab
- Advancing DNA-based antibody therapeutics through evaluation and characterization of in vivo expression, complex antibody formats, and delivery formulationsFrom1 Sep 2020 → TodayFunding: FWO fellowships, Foundations, funds and other with scientific goal
- Anti-tau intrabodies for the treatment of Alzheimer’s diseaseFrom1 Feb 2020 → 19 Feb 2024Funding: Baekeland
- Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE)From1 Jan 2020 → 31 Dec 2023Funding: FWO Strategic Basic Research (SBO)
- An on-chip single B cell mining platform for rapid development of fully human therapeutic antibodies and for immunoprofiling human antibody responsesFrom1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
- Development and validation of sampling and rapid assay methods for vedozilumab and ustekinumab therapeutic drug monitoringFrom1 Dec 2018 → 30 Nov 2020Funding: Foreign private sponsor - undefined
- BIOLOPTIM: implementing therapeutic drug monitoring of biologics for psoriasis and hidradenitis suppurativaFrom1 Oct 2018 → TodayFunding: FWO Applied Biomedical Research (TBM)
Publications
31 - 40 of 197
- Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition(2020)
Authors: Machteld Sillen, Paul Declerck
- Editorial: Gastrointestinal 2020: Novel inflammatory bowel disease treatments and therapeutic drug monitoring(2020)
Authors: Paul Declerck
Pages: III - VI - Electroporation outperforms in vivo-jetPEI for intratumoral DNA-based reporter gene transfer(2020)
Authors: Liesl Jacobs, Nick Geukens, Paul Declerck, Kevin Hollevoet
- The Efficacy, Safety, and Immunogenicity of Switching Between Reference Biopharmaceuticals and Biosimilars: A Systematic Review(2020)
Authors: Liese Barbier, Paul Declerck, Steven Simoens, Arnold Vulto, Isabelle Huys
Pages: 734 - 755 - Site-directed conjugation chemistry of the hexahistidine tag(2020)
Authors: Frederik Cleeren, Nick Geukens, Paul Declerck, Guy Bormans
Pages: S670 - S670 - A multifaceted view on market access of biosimilars(2020)
Authors: Evelien Moorkens, Isabelle Huys, Paul Declerck, Arnold Vulto
- Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity(2020)
Authors: Machteld Sillen, Sergei Strelkov, Paul Declerck
- Building a Versatile and Clinically Translatable Platform for DNA-Based Antibody Therapeutics(2020)
Authors: Kevin Hollevoet, Elien De Smidt, Giles Vermeire, Liesl Jacobs, Stephanie De Vleeschauwer, Nick Geukens, Paul Declerck
Pages: 237 - 238 - DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure(2020)
Authors: Liesl Jacobs, Nick Geukens, Paul Declerck, Kevin Hollevoet
Pages: 1068 - 1077 - Expanding a portfolio of (FO-) SPR surface chemistries with the Co(III)-NTA oriented immobilization of His6-tagged bioreceptors for applications in complex matrices(2020)
Authors: Sara Horta, Filip Delport, Machteld Sillen, Nick Geukens, Karen Vanhoorelbeke, Paul Declerck, Jeroen Lammertyn, Dragana Spasic
Pages: 960 - 969
Patents
1 - 1 of 1
- Dual targeting of tafi and pai-1 (Inventor)
Linked dataset
1 - 1 of 1