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Researcher
Paul Declerck
- Disciplines:Laboratory medicine, Regenerative medicine, Other basic sciences, Other health sciences, Other medical and health sciences, Medical biotechnology, Drug discovery and development, Pharmaceutics
Affiliations
- Therapeutic and Diagnostic Antibodies (Division)
Member
From1 Apr 2013 → 30 Sep 2023
Projects
1 - 10 of 28
- An integrated platform for the identification, isolation and characterization of human clock antibodies.From1 Jul 2021 → TodayFunding: Department Coordination
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- A Pharmacometrics Approach to Improve Dose Individualisation Methods of Biologicals in Patients with Chronic Inflammatory DiseasesFrom13 Oct 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Development and streamlining a validation and implementation workflow for model-informed precision dosing for biologicals and antimicrobialsFrom1 Oct 2020 → 30 Sep 2022Funding: IOF - technology validation in lab
- Advancing DNA-based antibody therapeutics through evaluation and characterization of in vivo expression, complex antibody formats, and delivery formulationsFrom1 Sep 2020 → TodayFunding: FWO fellowships, Foundations, funds and other with scientific goal
- Anti-tau intrabodies for the treatment of Alzheimer’s diseaseFrom1 Feb 2020 → 19 Feb 2024Funding: Baekeland
- Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE)From1 Jan 2020 → 31 Dec 2023Funding: FWO Strategic Basic Research (SBO)
- An on-chip single B cell mining platform for rapid development of fully human therapeutic antibodies and for immunoprofiling human antibody responsesFrom1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
- Development and validation of sampling and rapid assay methods for vedozilumab and ustekinumab therapeutic drug monitoringFrom1 Dec 2018 → 30 Nov 2020Funding: Foreign private sponsor - undefined
- BIOLOPTIM: implementing therapeutic drug monitoring of biologics for psoriasis and hidradenitis suppurativaFrom1 Oct 2018 → TodayFunding: FWO Applied Biomedical Research (TBM)
Publications
141 - 150 of 197
- Glycosylation influences the stability of human plasminogen activator inhibitor-1(2012)
Authors: Paul Declerck, Ann Gils
Pages: 570 - 572 - Increased zymogen activity of thrombin-activatable fibrinolysis inhibitor prolongs clot lysis(2012)
Authors: Niraj Mishra, Karlien Buelens, S Theyskens, Griet Compernolle, Ann Gils, Paul Declerck
Pages: 1091 - 1099 - TAFI deficiency plays a predominant role in the hyperfibrinolytic state observed in mice with combined TAFI and PAI-1 gene deficiency(2012)
Authors: E Vercauteren, M Peeters, Marc Hoylaerts, Roger Lijnen, JCM Meijers, Paul Declerck, Ann Gils
Pages: E19 - E19 - TAFI structure and function(2012)
Authors: Paul Declerck
Pages: E27 - E27 - Increased zymogen activity of thrombin-activatable fibrinolysis inhibitor prolongs clot lysis(2012)
Authors: Niraj Mishra, Ann Gils, Paul Declerck
Pages: 1091 - 1099 - Maximal PAI-1 inhibition in vivo requires neutralizing antibodies that recognize and inhibit glycosylated PAI-1(2012)
Authors: Ilse Scroyen, Roger Lijnen, Paul Declerck, Ann Gils
Pages: E126 - E133 - Convalescent plasma levels of TAFI activation peptide predict death and recurrent vascular events in ischemic stroke survivors(2012)
Authors: Ann Gils, Paul Declerck
Pages: 725 - 727 - Biologicals and biosimilars: a review of the science and its implications(2012)
Authors: Paul Declerck
Pages: 13 - 16 - Factor VII-activating protease promotes the proteolysis and inhibition of tissue factor pathway inhibitor(2012)
Authors: Paul Declerck
Pages: 427 - 33 - Development of a sandwich-type ELISA for the detection of human active thrombin activatable fibrinolysis inhibitor (TAFIa)(2012)
Authors: Maarten Hendrickx, Ann Gils, Paul Declerck
Pages: E4 - E4
Patents
1 - 1 of 1
- Dual targeting of tafi and pai-1 (Inventor)
Linked dataset
1 - 1 of 1