Researcher
Paul Cos
- Research Expertise:In vitro and in vivo biofilm assays, Integrated antimicrobial (bacteria, fungi, yeasts and parasites) screening and profiling of pure compounds and extracts, targeting redox homeostasis in mycobacteria
- Keywords:MICROBIOLOGY, BACTERIOLOGY, BIOFILMS, INFLAMMATION, Pharmacy and pharmacology
- Disciplines:Microbiology, Systems biology, Laboratory medicine
- Research techniques:In vitro and in vivo (pre-clinical) models of infectious diseases (bacteria and fungi), evaluation of drugs
- Users of research expertise:Pharmaceutical companies (big pharma, SME, spin-off), news agencies, journalists, government agencies, regulatory (EU) agencies, non-governmental organisations in the field of infectious diseases
Affiliations
- Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Responsible
From1 Oct 2020 → Today - Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Member
From1 Oct 2006 → 30 Sep 2020
Projects
1 - 10 of 59
- SEP BOF 2022 - DelNAM PlusFrom1 Dec 2022 → TodayFunding: BOF - projects
- Prevention of ventilator-associated pneumonia: analysis of the in vitro and in vivo anti-biofilm capacity of cecropin-based coatings on endotracheal tubes.From1 Nov 2022 → TodayFunding: FWO fellowships
- Chemical probes for imaging bacterial proteases in lung infections.From1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
- Respiratory co-infection models for fundamental and translational biomedical research.From1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
- Infrastructure for Diverse Applications of Single Cell Sorting and Dispensing using Microfluidics.From1 Jun 2022 → TodayFunding: BOF - scientific equipment program
- Implementation of in vivo models to identify potential candidates for treatment of Dry Eye DiseaseFrom1 Oct 2021 → 30 Sep 2022Funding: BOF - projects
- Persistence in Streptococcus pneumoniae infections: elucidation of the importance of persister cells in chronic and recurrent infectionsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- In vivo evaluation of biofilm-related pneumonia.From1 Oct 2020 → 30 Sep 2021Funding: BOF - projects
- Springboard for excellence in advanced development of antibacterials (SPRINGBOARD).From1 Sep 2020 → TodayFunding: H2020-EU.4. - Spreading excellence and widening participation
- 3D printing of drug loaded medical devices for personalized medicine.From1 May 2020 → 30 Apr 2022Funding: IOF - technology concept exploration
Publications
41 - 50 of 272
- Molecular docking study of flavonoids to block the aryl hydrocarbon receptor(2021)
Authors: Oscar Collado García, Hans De Winter, Paul Cos, Maria João Matos, Eugenio Uriarte, Gabriel Llaurado Maury, Jorrit De Waele, Glay Chinea Santiago, Enrique Molina
Pages: 1 - 16 - Antifungal activity of extracts, fractions, and constituents from Coccoloba cowellii leaves(2021)
Authors: Daniel Méndez, Julio C. Escalona-Arranz, Enrique Molina Pérez, Kenn Foubert, Emmy Tuenter, Ann Cuypers, Paul Cos, Luc Pieters
- Antiplasmodial oleanane triterpenoids from Terminalia albida root bark(2021)
Authors: Mamadou Balde, Emmy Tuenter, Mohamed S. Traoré, Laura Peeters, Paul Cos, Guy Caljon, Tom Vermeyen, Wouter Herrebout, Aliou M. Balde, Kenn Foubert, et al.
Pages: 666 - 675 - Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors(2021)
Authors: Dries De Ruysscher, Luping Pang, Stijn M.G. Lenders, Davie Cappoen, Paul Cos, Jef Rozenski, Sergei V. Strelkov, Stephen D. Weeks, Arthur Van Aerschot
- Gaining a better understanding of the extrusion process in fused filament fabrication 3D printing(2021)
Authors: Bahaa Shaqour, Mohammad Abuabiah, Salameh Abdel-Fattah, Adel Juaidi, Ramez Abdallah, Waleed Abuzaina, Mohammad Qarout, Bart Verleije, Paul Cos
Pages: 1279 - 1291 - Can filaments, pellets and powder be used as feedstock to produce highly drug-loaded ethylene-vinyl acetate 3D printed tablets using extrusion-based additive manufacturing?(2021)
Authors: Aseel Samaro, Bahaa Shaqour, Niloofar Moazami Goudarzi, Michael Ghijs, Ludwig Cardon, Matthieu N. Boone, Bart Verleije, Koen Beyers, Valérie Vanhoorne, Paul Cos, et al.
- Coupling additive manufacturing with hot melt extrusion technologies to validate a ventilator-associated pneumonia mouse model(2021)
Authors: Bahaa Shaqour, Juliana Aizawa Porto de Abreu, Clara Guarch-Pérez, Żaneta Górecka, Lars Christophersen, Wim Martinet, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, et al.
- Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida(2021)
Authors: Mamadou Balde, Emmy Tuenter, Mohamed Sahar Traoré, Paul Cos, Louis Maes, Aïssata Camara, Mamadou Saliou Telly Diallo, Elhadj Saïdou Baldé, Mamadou Aliou Balde, Luc Pieters, et al.
- Differential induction pattern towards classically activated macrophages in response to an immunomodulatory extract from Pleurotus ostreatus mycelium(2021)
Authors: Gabriel Llauradó Maury, Humberto Morris-Quevedo, Annick Heykers, Ellen Lanckacker, Davie Cappoen, Peter Delputte, Wim Vanden Berghe, Zelen Salgueiro, Paul Cos
- Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors(2021)
Authors: Lijun Song, Romain Merceron, Fabian Hulpia, Ainhoa Lucía, Begoña Gracia, Yanlin Jian, Martijn D.P. Risseeuw, Toon Verstraelen, Paul Cos, José A. Aínsa, et al.
Patents
1 - 5 of 5
- Compositions against candida infections (Inventor)
- Bis(acetamidophenyl) guanidinophenyethylphosphonates for use in the prevention and/or treatment of PAR-related diseases. (Inventor)
- Bis(acetamidophenyl) guanidinophenylethylphosphonates for use in the prevention and/or treatment of par-related diseases (Inventor)
- Compositions against candida infections (Inventor)
- Bis(acetamidophenyl) guanidinophenylethylphosphonates for use in the prevention and/or treatment of par-related diseases (Inventor)
Linked dataset
1 - 1 of 1