Researcher
Paul Cos
- Research Expertise:In vitro and in vivo biofilm assays, Integrated antimicrobial (bacteria, fungi, yeasts and parasites) screening and profiling of pure compounds and extracts, targeting redox homeostasis in mycobacteria
- Keywords:MICROBIOLOGY, BACTERIOLOGY, BIOFILMS, INFLAMMATION, Pharmacy and pharmacology
- Disciplines:Microbiology, Systems biology, Laboratory medicine
- Research techniques:In vitro and in vivo (pre-clinical) models of infectious diseases (bacteria and fungi), evaluation of drugs
- Users of research expertise:Pharmaceutical companies (big pharma, SME, spin-off), news agencies, journalists, government agencies, regulatory (EU) agencies, non-governmental organisations in the field of infectious diseases
Affiliations
- Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Responsible
From1 Oct 2020 → Today - Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Member
From1 Oct 2006 → 30 Sep 2020
Projects
1 - 10 of 59
- SEP BOF 2022 - DelNAM PlusFrom1 Dec 2022 → TodayFunding: BOF - projects
- Prevention of ventilator-associated pneumonia: analysis of the in vitro and in vivo anti-biofilm capacity of cecropin-based coatings on endotracheal tubes.From1 Nov 2022 → TodayFunding: FWO fellowships
- Chemical probes for imaging bacterial proteases in lung infections.From1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
- Respiratory co-infection models for fundamental and translational biomedical research.From1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
- Infrastructure for Diverse Applications of Single Cell Sorting and Dispensing using Microfluidics.From1 Jun 2022 → TodayFunding: BOF - scientific equipment program
- Implementation of in vivo models to identify potential candidates for treatment of Dry Eye DiseaseFrom1 Oct 2021 → 30 Sep 2022Funding: BOF - projects
- Persistence in Streptococcus pneumoniae infections: elucidation of the importance of persister cells in chronic and recurrent infectionsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- In vivo evaluation of biofilm-related pneumonia.From1 Oct 2020 → 30 Sep 2021Funding: BOF - projects
- Springboard for excellence in advanced development of antibacterials (SPRINGBOARD).From1 Sep 2020 → TodayFunding: H2020-EU.4. - Spreading excellence and widening participation
- 3D printing of drug loaded medical devices for personalized medicine.From1 May 2020 → 30 Apr 2022Funding: IOF - technology concept exploration
Publications
31 - 40 of 272
- LC-MS characterization and biological activities of Cuban cultivars of Plectranthus neochilus Schltr(2022)
Authors: Annarli O. Rodríguez-Ferreiro, Ania Ochoa-Pacheco, Daniel Méndez-Rodriguez, Emilia Ortiz-Beatón, Oneida Font-Salmo, Frenkel Guisado-Bourzac, Silvia Molina-Bertrán, Lianet Monzote, Paul Cos, Kenn Foubert, et al.
- Biofilm-related pneumonia(2022)
Authors: Juliana Aizawa Porto de Abreu, Paul Cos
Number of pages: 264 - Antiplasmodial activity of alkaloids from Croton linearis leaves(2022)
Authors: Jesús García Díaz, Emmy Tuenter, Julio Cesar Escalona Arranz, Gabriel Llauradó Maury, Paul Cos, Luc Pieters
Pages: 1 - 4 - Inhibitory effect on nitric oxide release in LPS-stimulated macrophages and free radical scavenging activity of Croton linearis Jacq. leaves(2022)
Authors: Jesus Garcia Diaz, Rosalia González Fernández, Julio César Escalona Arranz, Gabriel Llauradó Maury, Daniel Méndez Rodríguez, Linda De Vooght, Enrique Molina, Emmy Tuenter, Luc Pieters, Paul Cos
Pages: 1 - 14 - Antibiotic tolerance indicative of persistence is pervasive among clinical Streptococcus pneumoniae isolates and shows strong condition dependence(2022)
Authors: Nele Geerts, Linda De Vooght, Ioannis Passaris, Peter Delputte, Bram Van den Bergh, Paul Cos
Pages: 1 - 15 - The search for novel treatment strategies for Streptococcus pneumoniae infections(2021)
Authors: Freya Cools, Peter Delputte, Paul Cos
- Chemical and pharmacological potential of Coccoloba cowellii, an endemic endangered plant from Cuba(2021)
Authors: Daniel Méndez, Julio C. Escalona-Arranz, Kenn Foubert, Anastasia Van der Auwera, Stefano Piazza, Ann Cuypers, Paul Cos, Luc Pieters
- Validation of UDPG:PP as an anti‐virulence drug target against Streptococcus pneumoniae infections using Galleria mellonella as an alternative in vivo model(2021)
Authors: Freya Cools, Paul Cos, Peter Delputte
Number of pages: 200 - Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods(2021)
Authors: Jontana Allkja, Frits van Charante, Juliana Aizawa Porto de Abreu, Ines Reigada, Clara Guarch-Perez, Jesus Augusto Vazquez-Rodriguez, Paul Cos, Tom Coenye, Adyary Fallarero, Sebastian A.J. Zaat, et al.
- Microbial symbionts of insects as a source of new antimicrobials(2021)
Authors: Laurence Van Moll, Jeroen De Smet, Paul Cos, Leen Van Campenhout
Pages: 562 - 579
Patents
1 - 5 of 5
- Compositions against candida infections (Inventor)
- Bis(acetamidophenyl) guanidinophenyethylphosphonates for use in the prevention and/or treatment of PAR-related diseases. (Inventor)
- Bis(acetamidophenyl) guanidinophenylethylphosphonates for use in the prevention and/or treatment of par-related diseases (Inventor)
- Compositions against candida infections (Inventor)
- Bis(acetamidophenyl) guanidinophenylethylphosphonates for use in the prevention and/or treatment of par-related diseases (Inventor)
Linked dataset
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