Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
41 - 50 of 56
- Lipid-mediated cilium loss in cancer cells as a novel driver of cellular autonomy and potential target for interventionFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- The P5 Type ATPase Atp13A2, a Parkinson associated gene, coordinates key trafficking mechanisms involved in the maintenance of cancer cell proteostasisFrom1 Oct 2012 → 16 Oct 2017Funding: BOF - Doctoral projects
- Immunogenic cancer cell death: From molecular determinants and immune responses to pre-clinical immunotherapy.From1 Oct 2012 → 30 Sep 2013Funding: BOF - Other initiatives
- Molecular Signaling in Cell Death and Inflammation: an integrative approach from basic mechanisms to disease models.From1 Apr 2012 → 31 Dec 2017Funding: IUAP-VII
- Cutaneous Malignant Melanome: the role of autophagy in chemotherapy-mediated immunogenic apoptosis.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Aeroacoustic design and analysis of advanced light-weight liner configurations for sound attenuation in ducted flowsFrom1 Oct 2011 → 18 Oct 2016Funding: IWT personal funding - strategic basic research grants
- The effects of the clinically applicable chemotherapeutics on the immunogenicity of melanoma cell death.From1 Oct 2010 → 31 Mar 2015Funding: Nonprofit institution or equivalents, BOF - Doctoral projects
- 'Danger-associated molecular patterns': revealing the molecular signals dictating the communication between dying cells with the immune system.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Study of pro-survival effects of increased lipogenesis in cancer cells: implications for carcinogenesis and therapy.From1 Oct 2009 → 18 Nov 2014Funding: FWO fellowships
- TUMOUR PROGRESSION OF CUTANEOUS SQUAMOUS CELL CARCINOMA: RESPONSE TO CHEMOTHERAPEUTICS AND REGULATION OF THE EPITHELIAL-MESENCHYMAL TRANSITION PROCESSFrom1 Aug 2009 → 28 Jan 2014Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 239
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2024)
Authors: Jelle Verhoeven, Patrizia Agostinis, Madhur Agrawal, Sandra Nuyts
- An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.(2024)
Authors: Apostolis Nikolakopoulos, Francesca Bosisio, Gabriele Bergers, Colinda Scheele, Patrizia Agostinis
Pages: 114020 - SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Chris Marine, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyond(2023)
Authors: Jenny Sprooten, Abhishek Garg, Susan Schlenner, Patrizia Agostinis
- Cellular and molecular features related to exceptional therapy response and extreme long-term survival in glioblastoma(2023)
Authors: Maxime Vanmechelen, Paul Clement, Jean-françois Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer
Pages: 11107 - 11126 - Apoptotic cell death in disease-Current understanding of the NCCD 2023(2023)
Authors: Patrizia Agostinis, Bart De Strooper, Abhishek Garg, Chris Marine
Pages: 1097 - 1154 - Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.