Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
31 - 40 of 56
- Regulation of vesicular trafficking in melanoma and its driving role in melanoma plasticity and progressionFrom5 Oct 2015 → 25 Feb 2021Funding: FWO fellowships
- Endoplasmic Reticulum Stress in Health and Disease.From1 Oct 2015 → 30 Sep 2019Funding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- Cell biology of the endo-/lysosomal proteostasis in cancer and neurodegeneration (LYSOCaN).From1 Oct 2015 → 30 Sep 2021Funding: BOF - Concerted Research Project from 1994
- Autophagy in melanoma lymphangiogenesis; role and therapeutic implications.From1 Jan 2015 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
- Role of autophagy in melanoma-driven lymphangiogenesis.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Exploiting MELanoma disease comPLEXity to address European research training needs in translational cancer systems biology and cancer systems medicine.From1 Dec 2014 → 30 Nov 2018Funding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- Relevance of autophagy in melanoma lymphangiogenesis.From1 Oct 2014 → 30 Sep 2015Funding: BOF - Other initiatives
- Immunogenic cell death (ICD) in cancer: From plasticity and discovery of immunogenic determinants to anticancer vaccination.From1 Oct 2013 → 30 Sep 2019Funding: FWO fellowships
- BNIP3 AND ITS ROLE IN MODULATING THE INTERFACE BETWEEN MELANOMA CELLS AND IMMUNE CELLSFrom16 Sep 2013 → 30 Sep 2018Funding: BOF - Doctoral projects, Private funding of national origin - undefined
- Damage-associated molecular patterns; are they bona fide immunogenic signals or do they simply assist/augment the antigenicity of cancer cells?From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 239
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2024)
Authors: Jelle Verhoeven, Patrizia Agostinis, Madhur Agrawal, Sandra Nuyts
- An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.(2024)
Authors: Apostolis Nikolakopoulos, Francesca Bosisio, Gabriele Bergers, Colinda Scheele, Patrizia Agostinis
Pages: 114020 - SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Chris Marine, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyond(2023)
Authors: Jenny Sprooten, Abhishek Garg, Susan Schlenner, Patrizia Agostinis
- Cellular and molecular features related to exceptional therapy response and extreme long-term survival in glioblastoma(2023)
Authors: Maxime Vanmechelen, Paul Clement, Jean-françois Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer
Pages: 11107 - 11126 - Apoptotic cell death in disease-Current understanding of the NCCD 2023(2023)
Authors: Patrizia Agostinis, Bart De Strooper, Abhishek Garg, Chris Marine
Pages: 1097 - 1154 - Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.