Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 56
- Harnessing lysosomal iron homeostasis to prevent melanoma disseminationFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Function of PERK in T cell metabolic reprogramming: deciphering its role as ER stress sensor vs its novel role as coordinator of membrane contact sitesFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding the spatio-temporal changes of the metastatic lymph node epicenterFrom11 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unfolding the role of Perk in T cell biology and metabolism: a matter of contact sites?From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Clinical, Immunological and Functional Study of ADA2 deficiencyFrom2 Aug 2021 → TodayFunding: FWO fellowships
- Autophagy in inflammation and inflammatory disorders (ATLANTIS), from basic insights to experimental therapy.From1 Jan 2021 → TodayFunding: BOF - iBOF
Publications
211 - 220 of 239
- Role of autophagy pathways in PDT, a ROS-based anti-cancer therapy(2011)
Authors: Michael Dewaele, Patrizia Agostinis, Peter de Witte
Number of pages: 126 - Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage(2011)
Authors: Michael Dewaele, Noemí Rubio Romero, Tom Verfaillie, Peter de Witte, Patrizia Agostinis
Pages: 1402 - 1414 - Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma(2010)
Authors: Sofie Claerhout, Lien Verschooten, Rita De Vos, Patrizia Agostinis, Maria Garmyn
Pages: 2790 - 2803 - ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy(2010)
Authors: Michael Dewaele, Hannelore Maes, Patrizia Agostinis
Pages: 838 - 54 - Photodynamic therapy: illuminating the road from cell death towards anti-tumour immunity(2010)
Authors: Abhishek Garg, Patrizia Agostinis
Pages: 1050 - 71 - The Flavonoid Luteolin Increases the Resistance of Normal, but Not Malignant Keratinocytes, Against UVB-Induced Apoptosis(2010)
Authors: Lien Verschooten, Patrizia Agostinis, Maria Garmyn
Pages: 2277 - 2285 - A p38MAPK - HIF-1 pathway initiated by UVB irradiation is required to induce Noxa and apoptosis of human keratinocytes(2010)
Authors: Kris Nys, An Van Laethem, Noemí Rubio Romero, Maria Garmyn, Patrizia Agostinis
Pages: 2269 - 2276 - An improved orthotopic rat bladder tumor model using Dil-loaded fluorescent AY-27 cells(2010)
Authors: Ben Van Cleynenbreugel, Hendrik Van Poppel, Evelyne Lerut, Patrizia Agostinis, Peter de Witte
Pages: 986 - 993 - SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity(2010)
Authors: Patrizia Agostinis
Pages: 821 - 32 - Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria(2010)
Authors: E Wirawan, L Vande Walle, K Kersse, S Cornelis, Sofie Claerhout, I Vanoverberghe, R Roelandt, R De Rycke, J Verspurten, W Declercq, et al.
Pages: e18