Researcher
Patrick Augustijns
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 43
- Effect of pH on colloidal structures in human intestinal fluids and intestinal absorption of anticancer drugsFrom1 Sep 2023 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- The impact of advanced age and age-related diseases on drug absorptionFrom10 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanistic in silico modelling of colonic drug absorptionFrom1 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PBPK modelling of drug absorption in elderlyFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving preclinical assays to enhance the prediction of the in vivo behavior of oral drug productsFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Towards enhanced translational colon-specific in vitro tissue models for assessment of drug disposition, metabolism and safetyFrom23 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Evaluating the impact of advanced age and age-related diseases on gastrointestinal drug behaviour and on the biochemical barrier of the intestinal mucosaFrom17 May 2021 → 2 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug disposition in healthy volunteers and colorectal cancer patientsFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multi-dimensional liquid chromatography for the analysis of complex samples.From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- Boosting advanced doctoral training in innovative colon targeting drugsFrom1 Jan 2021 → TodayFunding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
Publications
321 - 330 of 377
- Drug Solubility in the Gastrointestinal Tract(2010)
Authors: Christos Reppas, Patrick Augustijns, JB Dressman, C Reppas
Pages: 155 - 167Number of pages: 13 - Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling(2010)
Authors: Joachim Brouwers, Pieter Annaert, Patrick Augustijns
Pages: 278 - 285 - Development and in vitro evaluation of gel-formulated saquinavir as vaginal microbicide: anti-HIV-1 activity and pharmaceutical availability in biorelevant media(2010)
Authors: Kurt Vermeire, Joachim Brouwers, Patrick Augustijns, Dominique Schols
Pages: A48 - A49 - Permeability Measurement(2010)
Authors: Joachim Brouwers, Pieter Annaert, Patrick Augustijns
Pages: 168 - 205Number of pages: 38 - Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich-cultured rat and human hepatocytes(2010)
Authors: Zhiwei Ye, Patrick Augustijns, Pieter Annaert
Pages: 178 - 188 - Ex vivo permeability experiments in excised rat intestinal tissue and in vitro solubility measurements in aspirated human intestinal fluids support age-dependent oral drug absorption(2010)
Authors: Pieter Annaert, Joachim Brouwers, Jan Tack, Patrick Augustijns
Pages: 15 - 22 - Effect of pH and comedication on intraluminal formulation behavior of posaconazole: monitoring of intraluminal drug concentrations in healthy volunteers(2010)
Authors: Jeroen Walravens, Joachim Brouwers, Jan Tack, Pieter Annaert, Patrick Augustijns
- Drug supersaturation in simulated and human intestinal fluids representing different nutritional states(2010)
Authors: Jan Bevernage, Joachim Brouwers, Sarah Clarysse, Pieter Annaert, Jan Tack, Patrick Augustijns
Pages: 4525 - 4534 - Growth of Itraconazole Nanofibers in Supersaturated Simulated Intestinal Fluid(2010)
Authors: Randy Mellaerts, Alexander Aerts, Jan Vermant, Guy Van den Mooter, Johan Martens, Patrick Augustijns
Pages: 905 - 913 - In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and FMO3(2010)
Authors: Souzan B Yanni, Pieter Annaert, Patrick Augustijns, Joseph G Ibrahim, Daniel K Benjamin Jr, Dhiren R Thakker
Pages: 25 - 31
Patents
1 - 1 of 1
- Permeability model (Inventor)