Researcher
Olivier De Wever
- Keywords:tumor models, tumor environment
- Disciplines:Cancer diagnosis, Cancer therapy, Cancer biology
Affiliations
- Department of Human Structure and Repair (Department)
Member
From1 Oct 2018 → Today - Department of Radiation oncology and experimental cancer research (Department)
Member
From1 Oct 1999 → 30 Sep 2018
Projects
11 - 20 of 36
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- IVIS Lumina III LT In Vivo imaging system.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Field-flow fractionation (FFF) system for combination with high-end ICP-mass spectrometry (ICP-MS).From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Identification of Low-Grade Serous Ovarian Carcinoma (LGSOC) therapeutics using clinical relevant spheroid and tumor-engineered models for peritoneal metastasis.From1 Nov 2020 → TodayFunding: FWO fellowships
- Targeting tumor microenvironment to counteract cancer progressionFrom1 Oct 2020 → TodayFunding: BOF - mobility
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Cancer invasion and metastasis: development of a new spheroid confrontation assay and preclinical characterisation of a novel inhibitory mechanismFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- beurs EVDS Arne Peirsman: Design of a 3D printed and perfused breast cancer metastasis model (3D PAP Be CAME model)From1 Oct 2018 → 30 Sep 2019Funding: Foundations, funds and other with scientific goal
- Targeting cancer-associated fibroblasts to overcome immunosuppressive mechanisms in mismatch repair-deficient tumorsFrom1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Tumor engineering a clinical relevant in vivo model for peritoneal metastasisFrom1 Oct 2018 → 30 Sep 2021Funding: FWO fellowships
Publications
1 - 10 of 77
- Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts(2024)
Authors: Suzanne Fischer, David Creytens, Stefanie Gijsels, Benedicte Descamps, Lore Lapeire, An Hendrix, Gwen Sys, Olivier De Wever
- Glioblastoma-associated mesenchymal stem/stromal cells and cancer-associated fibroblasts : partners in crime?(2024)
Authors: Thibault Lootens, Bart Roman, Christian Stevens, Olivier De Wever, Robrecht Raedt
- Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification(2023)
Authors: Fien Gysens, Lisa Ostyn, Ellen Goeteyn, Eva Blondeel, Justine Nuytens, Olivier De Wever, Eric de Bony de Lavergne, Aurélie Crabbé, Pieter Mestdagh
- Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis(2023)
Authors: Teresa González-Muñoz, Angela Di Giannatale, Susana García-Silva, Vanesa Santos, Sara Sánchez-Redondo, Claudia Savini, Osvaldo Graña-Castro, Carmen Blanco-Aparicio, Suzanne Fischer, Olivier De Wever, et al.
Pages: 3744 - 3758 - Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer(2023)
Authors: Cristina Muntean, Eva Blondeel, Laure Harinck, Kunal Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan De Smedt, Katrien Remaut, Koen Raemdonck
- Histologic tumor type as a determinant of survival in hormone receptor-positive, HER2-negative, pT1-3 invasive ductal and lobular breast cancer(2023)
Authors: Menekse GOKER, Hannelore Denys, An Hendrix, Olivier De Wever, Koen Van de Vijver, Geert Braems
- A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment(2023)
Authors: Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, et al.
- Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles(2023)
Authors: Quentin Roux, Robin Boiy, Felix De Vuyst, Mercedes Tkach, Cláudio Pinheiro, Sofie De Geyter, Ilkka Miinalainen, Clotilde Thery, Olivier De Wever, An Hendrix
Patents
1 - 5 of 5
- Use of bacterial extracellular vesicles as a biomarker for intestinal barrier permeability and microbial dysbiosis (Inventor)
- Targeting quorum-sensing peptides for diagnosis, treatment and/or prevention of colorectal cancer metastasis (Inventor)
- Use of bacterial extracellular vesicles as a biomarker for intestinal barrier permeability and microbial dysbiosis (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)