Researcher
Nico Callewaert
- Keywords (Ghent University):medical biotechnology, protein engineering
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics
- Disciplines (Ghent University):Infectious diseases, Proteins, Systems biology not elsewhere classified, Cell, tissue and organ engineering, Protein diagnostics, Medical biotechnology diagnostics, Medical molecular engineering of nucleic acids and proteins, Molecular biophysics, Microbiology not elsewhere classified, Immunology not elsewhere classified
- See also: Nico Callewaert (Flanders Institute for Biotechnology)
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - VIB-UGent Center for Medical Biotechnology (Research Center)
Responsible
From1 Jan 2017 → Today - Callewaert Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biochemistry (Department)
Member
From1 May 2014 → 30 Sep 2018 - Department of Biochemistry and microbiology (Department)
Member
From1 Oct 2006 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 1998 → 30 Apr 2009
Projects
21 - 30 of 35
- Role of glycosylation in the immunogenicity of the nematode specific activation-associated secreted proteins (ASPs) and its implication in vaccine efficacy.From1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- SECRiFY: a new tool for studying eukaryotic protein secretion.From1 Oct 2019 → 1 Nov 2019Funding: BOF - doctoral mandates
- Replacement of N-glycan analysis equipmentFrom1 Jun 2018 → 31 May 2020Funding: BOF - Other initiatives
- Customized glycosylation engineering to enhance lysosomal enzyme delivery to muscle tissue in congenital and acquired lysosomal dysfunction.From1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Understanding and exploiting glycosylation in immunotherapy.From1 Jan 2017 → 31 Oct 2021Funding: BOF - Concerted Research Project from 1994
- Glyco(Double)Delete technology: maturation, development of compatible GlyConnect coupling technologyFrom1 Feb 2016 → 31 Oct 2018Funding: IOF - Industrial Research Fund
- Bio-encapsulation in yeast for delivery of intestinal epithelium-protecting and microbiome-manipulating biopharmaceuticalsFrom1 Jan 2016 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
- Improved glycoconjugate purification using temperature-controlled lectin multimersFrom1 Oct 2014 → 30 Apr 2016Funding: IOF - Industrial Research Fund
- ERC Professorship: GlycoTargetFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - ZAP BOF mandates
- GlycoCirrhoTest: manufacturing demonstration, CE mark preparation and establishing link to pathology of cirrhotic liver regeneration.From1 Jul 2013 → 30 Jun 2016Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 23
- Modulating antibody effector functions by Fc glycoengineering(2023)
Authors: Mikel García-Alija, Berre Van Moer, Diego E. Sastre, Tala Azzam, Jonathan J. Du, Beatriz Trastoy, Nico Callewaert, Eric J. Sundberg, Marcelo E. Guerin
- A metabolic gene survey pinpoints fucosylation as a key pathway underlying the suppressive function of regulatory T cells in cancer(2023)
Authors: Sotiria Pinioti, Himal Sharma, Nina C. Flerin, Qian Yu, Amalia Tzoumpa, Sarah Trusso Cafarello, Elien De Bousser, Nico Callewaert, Guillaume Oldenhove, Susan Schlenner, et al.
Pages: 1611 - 1629 - The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates(2022)
Authors: Andreia Sofia da Costa de Monica Ferreira, Ines Royaux, Jian Liu, Zhangjie Wang, Guowei Su, Diederik Moechars, Nico Callewaert, Louis De Muynck
- Epidermal galactose spurs chytrid virulence and predicts amphibian colonization(2021)
Authors: Yu Wang, Elin Verbrugghe, Leander Meuris, Koen Chiers, Moira Kelly, Nico Callewaert, Frank Pasmans, An Martel
- Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity(2021)
Authors: Fabien Henri Thery, Lia Martina, Caroline Asselman, Heidi Repo, Y Zhang, Koen Sedeyn, Georgios Moschonas, C Bredow, QW Teo, J Zhang, et al.
- Engineering of yeast glycoprotein expression(2021)
Authors: Charlot De Wachter, Linde Van Landuyt, Nico Callewaert, Erdmann Rapp, Udo Reichl
Pages: 93 - 135 - Development of a counterselectable transposon to create markerless knockouts from an 18,432-clone ordered Mycobacterium bovis bacillus Calmette-Guérin mutant resource(2020)
Authors: Katlyn Borgers, Kristof Vandewalle, Annelies Van Hecke, Gitte Michielsen, Evelyn Plets, Loes van Schie, Sandrine Vanmarcke, Laurent Schindfessel, Nele Festjens, Nico Callewaert
- Prostate protein n-glycosylation profiling by means of DNA sequencer-assisted fluorophore-assisted carbohydrate electrophoresis(2019)Edition: 2nd ed.Series: Methods in Molecular Biology
Authors: Tijl Vermassen, Nico Callewaert, Sylvie Rottey, Joris Delanghe, Terry M Phillips
Pages: 235 - 250 - N-Linked glycosylation and near-infrared spectroscopy in the diagnosis of prostate cancer(2019)
Authors: Tijl Vermassen, Sander De Bruyne, Jonas Himpe, Nicolaas Lumen, Nico Callewaert, Sylvie Rottey, Joris Delanghe
- Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine(2019)
Authors: Katlyn Borgers, Jheng-Yang Ou, Po-Xing Zheng, Petra Tiels, Annelies Van Hecke, Evelyn Plets, Gitte Michielsen, Nele Festjens, Nico Callewaert, Yao-Cheng Lin
Patents
1 - 10 of 10
- Compositions for use to treat cataract (Inventor)
- Means and methods for amplifying nucleotide sequences (Inventor)
- Means and methods for monitoring inflammation (Inventor)
- Improved aminopeptidases for single molecule peptide sequencing (Inventor)
- GLYCOSYLATED SINGLE CHAIN IMMUNOGLOBULIN DOMAINS (Inventor)
- Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof (Inventor)
- Cells producing glycoproteins having altered N- and O-glycosylation patterns and methods and use (Inventor)
- Means and methods for generating complex glycans derived from fungal engineered hosts (Inventor)
- Means and methods for single molecule peptide sequencing (Inventor)
- Means and methods for amplifying nucleotide sequences (Inventor)