Researcher
Nico Callewaert
- Keywords (Ghent University):medical biotechnology, protein engineering
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics
- Disciplines (Ghent University):Infectious diseases, Proteins, Systems biology not elsewhere classified, Cell, tissue and organ engineering, Protein diagnostics, Medical biotechnology diagnostics, Medical molecular engineering of nucleic acids and proteins, Molecular biophysics, Microbiology not elsewhere classified, Immunology not elsewhere classified
- See also: Nico Callewaert (Ghent University)
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - VIB-UGent Center for Medical Biotechnology (Research Center)
Responsible
From1 Jan 2017 → Today - Callewaert Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biochemistry (Department)
Member
From1 May 2014 → 30 Sep 2018 - Department of Biochemistry and microbiology (Department)
Member
From1 Oct 2006 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 1998 → 30 Apr 2009
Projects
1 - 5 of 5
- Targeting of glycosylation pathways to empower CAR-T therapy of solid tumors (GlycoCAR) (ERC Advanced Grant).From1 Jul 2023 → TodayFunding: HORIZON.1.1 - European Research Council (ERC)
- VIB Grant for Callewaert Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- Pichia for pandemic readiness VHH-Fc antibodiesFrom1 Dec 2021 → 29 Feb 2024Funding: Foreign foundations, funds with scientific view
- ExeVir's XVR011, a best in class nanobody-based biology that broadly neutralizes SARS-COV-1 and SARS-COV-2From1 Dec 2021 → 30 Nov 2022Funding: Other EU initiatives out of framework
- VIB Grant for Callewaert Lab_Period:2017-01-01-2021-12-31From1 Jan 2017 → 31 Dec 2021Funding: FRI - Project driven research
Publications
1 - 10 of 50
- Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.(2024)
Authors: Bert Schepens, Sieglinde De Cae, Koen Sedeyn, Hannah Eeckhaut, Daria Fijalkowska, Kenny Roose, Nico Callewaert, Han Remaut, Xavier Saelens
Pages: 104960 - GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery.(2023)
Authors: Loes van Schie, Wander Van Breedam, Charlotte Roels, Bert Schepens, Iebe Rossey, Karel Thooft, Xavier Saelens, Nico Callewaert
Pages: 2210709 - A Metabolic Gene Survey Pinpoints Fucosylation as a Key Pathway Underlying the Suppressive Function of Regulatory T Cells in Cancer.(2023)
Authors: Sotiria Pinioti, Himal Sharma, Nina Flerin, Elien De Bousser, Nico Callewaert, Mario di Matteo, Massimiliano Mazzone
Pages: 1611-1629 - Systematic review: Glycomics as diagnostic markers for hepatocellular carcinoma.(2023)
Authors: Leander Meuris, Nico Callewaert
Pages: 23-38 - Modulating antibody effector functions by Fc glycoengineering.(2023)
Authors: Berre Van Moer, Nico Callewaert
Pages: 108201 - Glycomics-based serum markers as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection.(2023)
Authors: Leander Meuris, Nico Callewaert
Pages: 96-102 - The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates.(2022)
Authors: Nico Callewaert
Pages: 61 - GlyConnect-Ugi: site-selective, multi-component glycoprotein conjugations through GlycoDelete expressed glycans.(2022)
Authors: Karel Thooft, Wander Van Breedam, Francis Santens, Simon Devos, Nico Callewaert
Pages: 464-471 - GENType: all-in-one preimplantation genetic testing by pedigree haplotyping and copy number profiling suitable for third-party reproduction.(2022)
Authors: Andries De Koker, Nico Callewaert
Pages: 1678-1691 - Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy.(2022)
Authors: Loes van Schie, Hendrik Grootaert, Simon Devos, Wannes Weyts, Nico Callewaert
Pages: 121772
Patents
1 - 10 of 10
- GLYCO-ENGINEERED YEAST FOR THERAPEUTIC PROTEIN PRODUCTION (Inventor)
- CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR BINDERS (Inventor)
- SARBECOVIRUS BINDERS (Inventor)
- ENGINEERED STABILIZING AGLYCOSYLATED FC-REGIONS (Inventor)
- CORONA VIRUS BINDERS (Inventor)
- GLYCO-ENGINEERED CAR-T CELLS (Inventor)
- NEUTRALIZING ANTI-SARS-COV-2 HUMAN ANTIBODIES (Inventor)
- CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR BINDERS FOR TARGETED PROTEIN DEGRADATION (Inventor)
- Improved aminopeptidases for single molecule peptide sequencing (Inventor)
- CORONA VIRUS BINDERS (Inventor)