Researcher
Nick Geukens
- Disciplines:Laboratory medicine, Medical biotechnology, Regenerative medicine, Other basic sciences, Other health sciences, Drug discovery and development, Pharmaceutics, Other medical and health sciences
Affiliations
- Therapeutic and Diagnostic Antibodies (Division)
Member
From15 May 2019 → Today - Chemistry, Kulak Kortrijk Campus (Department)
Member
From1 Sep 2009 → 14 May 2019 - Faculty of Science, Kulak Kortrijk Campus (Faculty)
Member
From14 Jul 2008 → 31 Aug 2009 - Laboratory of Molecular Bacteriology (Rega Institute) (Division)
Member
From1 Oct 1999 → 13 Jul 2008
Projects
1 - 10 of 23
- Next generation immunotherapy solutions against macrophages to overcome cancer immuno-resistanceFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- A novel targeted therapy to treat bleeding in patients with a left ventricular assist device.From1 May 2023 → TodayFunding: IOF - mandates
- Flow cytometer for the Interdisciplinary Research Facility Life Sciences at Campus Kulak KortrijkFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Next-generation DNA vectors to improve efficacy, precision and accessibility of antibody gene transferFrom15 Mar 2022 → 14 Mar 2024Funding: BOF - various
- Targeted mass spectrometry-based quantification of autoantibodies in systemic rheumatic diseasesFrom1 Oct 2021 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Rational design of biologics for therapeutic development (FoldCo)From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Why dose lung damage sometimes continue to worsen after the body seems to have cleared the SARS-CoV-2 virus?From1 Oct 2021 → 31 Mar 2023Funding: Foreign private sponsor - undefined
- Unraveling of protective innate and adaptive immune responses to SARS-CoV-2 in the setting of HCoV crossreactivityFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
Publications
11 - 20 of 65
- Point-of-care therapeutic drug monitoring of adalimumab by integrating a FO-SPR biosensor in a self-powered microfluidic cartridge(2022)
Authors: Henry Ordutowski, Charlotte Van Tricht, Mattijs Bulcaen, Marta Ciwinska, Caro Gutierrez Cisneros, Xander Janssens, Nick Geukens, Debby Thomas, Francesco Dal Dosso, Dragana Spasic, et al.
- High Incidence of SARS-CoV-2 Variant of Concern Breakthrough Infections Despite Residual Humoral and Cellular Immunity Induced by BNT162b2 Vaccination in Healthcare Workers: A Long-Term Follow-Up Study in Belgium(2022)
Authors: Bas Calcoen, Winnie Kerstens, Maya Imbrechts, Thomas Vercruysse, Kai Dallmeier, Johan Van Weyenbergh, Piet Maes, Xavier Bossuyt, Hendrik Jan Thibaut, Karen Vanhoorelbeke, et al.
- Development and validation of a microfluidic multiplex immunoassay for the determination of levels and avidity of serum antibodies to tetanus, diphtheria and pertussis antigens(2022)
Authors: Debby Thomas, Maaike Cockx, Louanne Ampofo, Nick Geukens, Xavier Bossuyt
- Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells(2022)
Authors: Benno Verbelen, Paulien Verstraete, Sonia Cinque, Maya Imbrechts, Nick Geukens, Daniele Pepe, Kim Kampen, Kim De Keersmaecker
Pages: 100 - 114 - Innovative FO-SPR Label-free Strategy for Detecting Anti-RBD Antibodies in COVID-19 Patient Serum and Whole Blood(2022)
Authors: Karen Leirs, Wim Maes, Maya Imbrechts, Katrien Lagrou, Nick Geukens, Jeroen Lammertyn, Dragana Spasic
Pages: 477 - 487 - Miniaturized single-cell technologies for monoclonal antibody discovery(2021)
Authors: Julie Van Lent, Jolien Breukers, Karen Ven, Louanne Ampofo, Maya Imbrechts, Nick Geukens, Karen Vanhoorelbeke, Paul Declerck, Jeroen Lammertyn
Pages: 3627 - 3654 - Improved Potency and Safety of DNA-Encoded Antibody Therapeutics Through Plasmid Backbone and Expression Cassette Engineering(2021)
Authors: Giles Vermeire, Nick Geukens, Paul Declerck, Kevin Hollevoet
Pages: 1200 - 1209 - DNA-based delivery of anti-DR5 Nanobodies improves exposure and anti-tumor efficacy over protein-based administration(2021)
Authors: Giles Vermeire, Nick Geukens, Paul Declerck, Kevin Hollevoet
Pages: 828 - 838 - Novel biosensing concepts for advancing antigen-specific antibody detection(2021)
Authors: Sara Horta, Karen Vanhoorelbeke, Jeroen Lammertyn, Nick Geukens
- Evaluation of Immuno-Rolling Circle Amplification for Multiplex Detection and Profiling of Antigen-Specific Antibody Isotypes(2021)
Authors: Sara Horta, Jolien Breukers, Nick Geukens, Karen Vanhoorelbeke, Jeroen Lammertyn
Pages: 6169 - 6177
Patents
1 - 5 of 5
- Screening and sorting of single cells (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
- Screening and sorting of single cells (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
Linked dataset
1 - 1 of 1