Researcher
Nathalie Cools
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Biological system engineering, Medical biotechnology, Hematology, Immunology, Molecular and cell biology, Neurosciences, Regenerative medicine
Affiliations
- Laboratory for Experimental Hematology (LEH) (Research group)
Member
From1 Jan 2019 → Today - Vaccine & Infectious Disease Institute (VAXINFECTIO) (Research group)
Member
From1 Oct 2007 → 31 Dec 2018
Projects
1 - 10 of 30
- Towards an Off-the-Shelf Therapy: Tolerogenic Dendritic Cell-derived Extracellular Vesicles for the Treatment of Multiple Sclerosis.From1 Dec 2022 → TodayFunding: IOF - technology concept exploration
- Towards an Off-the-Shelf Therapy: Tolerogenic Dendritic Cell-derived Extracellular Vesicles for the Treatment of Multiple Sclerosis.From1 Nov 2022 → TodayFunding: VITO (Flemish Institute for Technological Research)
- Integrative omics approach to identify the mechanism of tolerance induction by tolerogenic dendritic cell derived extracellular vesicles in multiple sclerosis.From1 Jan 2022 → TodayFunding: Foundations, funds and other with scientific goal
- Flow Cytometry and Cell Sorting Core Facility Uantwerpen (FACSUA)From1 Jan 2022 → TodayFunding: BOF - research organisations
- VAXINFECTIO-PD _ VAXINFECTIO: Vaccine & Infectious Disease Institute _ PD: Product Development.From1 Jan 2021 → TodayFunding: IOF - mandates
- BDNF-engineered regulatory T cells, a future regenerative cell-therapeutic strategy in progressive MS.From1 Jan 2021 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Approaching multiple sclerosis from a computational perspective through bioinformatic analysis of the T-cell repertoire.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Engaging the immune system for remyelination in the brain using BDNF-engineered regulatory T cells.From1 Oct 2020 → TodayFunding: BOF - doctoral mandates
- INnovative Training in Myeloid Regulatory Cell Therapy (INsTRuCT).From1 Jan 2020 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Deep Sequencing of myelin-reactive T-cells to elucidate new disease mechanisms and identify correlates for treatment responsiveness.From1 Jan 2020 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 88
- Targeted tolerance in multiple sclerosis(2023)
Authors: Ibo Janssens, Nathalie Cools, Inez Wens
Number of pages: 272 - Neurotrophic factors as regenerative therapy for neurodegenerative diseases(2023)
Authors: Jasper Van den Bos, Barbara Willekens, Nathalie Cools, Inez Wens
Pages: 1 - 24 - A microfluidic in vitro three-dimensional dynamic model of the blood-brain barrier to study the transmigration of immune cells(2022)
Authors: Megha Meena, Robin Vandormael, Maxime De Laere, Isabel Pintelon, Zwi Berneman, Regan Watts, Nathalie Cools
- Understanding and design of a novel dynamic biomimetic blood-brain barrier model(2022)
Authors: Megha Meena, Nathalie Cools
Number of pages: 256 - Impact of maternal pertussis antibodies on the infants’ cellular immune responses(2022)
Authors: Marjolein Orije, Irene García-Fogeda, Wouter Van Dyck, Véronique Corbière, Françoise Mascart, Ludo Mahieu, Niel Hens, Pierre Van Damme, Nathalie Cools, Benson Ogunjimi, et al.
Pages: 442 - 452 - Treatment of in vitro generated Langerhans cells with JAK-STAT inhibitor reduces their inflammatory potential(2022)
Authors: Ann Sterkens, Ibo Janssens, Megha Meena, Hans De Reu, Laura Van Bruggen, Julien Lambert, An Bervoets, Nathalie Cools
Pages: 1 - 12 - Cells infected with human papilloma pseudovirus display nuclear reorganization and heterogenous infection kinetics(2022)
Authors: Freya Molenberghs, Marlies Verschuuren, Michaël Barbier, Johannes Bogers, Nathalie Cools, Peter Delputte, Mario Schelhaas, Winnok De Vos
Pages: 1035 - 1048 - Are cell-based therapies safe and effective in the treatment of neurodegenerative diseases? A systematic review with meta-analysis(2022)
Authors: Jasper Van den Bos, Nathalie Cools, Inez Wens
Pages: 1 - 27 - Engineering of regulatory T cells by means of mRNA electroporation in a GMP-compliant manner(2022)
Authors: Ibo Janssens, Diana Campillo Davó, Jasper Van den Bos, Hans De Reu, Zwi Berneman, Inez Wens, Nathalie Cools
Pages: 1 - 14 - Tolerogenic dendritic cells induce apoptosis-independent T cell hyporesponsiveness of SARS-CoV-2-specific T cells in an antigen-specific manner(2022)
Authors: Mats Van Delen, Ibo Janssens, Amber Dams, Laurence Roosens, Benson Ogunjimi, Zwi Berneman, Judith Derdelinckx, Nathalie Cools
Pages: 1 - 15