Researcher
Mohamed Lamkanfi
- Keywords:Cell death and inflammation
- Disciplines:Immunology not elsewhere classified, Cell signalling, Applied immunology, Innate immunity, Autoimmunity, Immunogenetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2015 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From5 Aug 2009 → 30 Sep 2015 - Research Department (Administrative office)
Member
From1 Jul 2005 → 30 Jun 2006 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2000 → 30 Sep 2004
Projects
1 - 10 of 28
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- A MESO QuickPlex SQ system to measure single or multiple immunotargets in biofluidsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Targeting NLRP3-mediated inflammation with novel chemotypesFrom1 Oct 2022 → 31 Mar 2024Funding: Horizon Europe - European Research Council (ERC)
- Cell Death Regulation and Role in Infection and Inflammatory DiseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Single cell analysis of inflammasome-mediated IL-1ß secretion in primary human monocytesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Regulation of the Nlrp1a inflammasome in cutaneous and systemic autoinflammationFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Mechanisms and regulation of inflammasome-associated programmed cell deathFrom1 Jan 2020 → 31 Dec 2021Funding: H2020 - Frontier Research (ERC)
- Investigating microglia inflammasome activation and regulation in
Alzheimer diseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research Grant
Publications
41 - 50 of 131
- A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation(2018)
Authors: Sofie Voet, Conor Mc Guire, Nora Hagemeyer, Arne Martens, Anna Schroeder, Peter Wieghofer, Carmen Daems, Ori Staszewski, Marta Joana Costa Jordao, Mozes Sze, et al.
- Gut sensor halts viral attack(2017)
Authors: Pedro Henrique Viana Saavedra, Mohamed Lamkanfi
Pages: 606 - 608 - Flagellin-mediated protection against intestinal Yersinia pseudotuberculosis infection does not require interleukin-22(2017)
Authors: Rémi Porte, Laurye Van Maele, Natalia Muñoz-Wolf, Benoit Foligné, Laure Dumoutier, Julien Tabareau, Delphine Cayet, Pierre Gosset, Nicolas Jonckheere, Isabelle Van Seuningen, et al.
- A new lead to NLRP3 inhibition(2017)
Authors: Mohamed Lamkanfi, Vishva M Dixit
Pages: 3147 - 3149 - Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections(2017)
Authors: M Hassane, Dieter Demon, D Soulard, J Fontaine, LE Keller, EC Patin, R Porte, I Prinz, B Ryffel, A Kadioglu, et al.
Pages: 1056 - 1068 - Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4(2017)
Authors: Nina Van Opdenbosch, Hanne Van Gorp, Maarten Verdonckt, Pedro Henrique Viana Saavedra, Nathalia Moraes de Vasconcelos, Amanda Gonçalves, Dieter Demon, Magdalena Matusiak, Filip Van Hauwermeiren, Jinke D'Hont, et al.
Pages: 3427 - 3444 - Gold nanodome SERS platform for label-free detection of protease activity(2017)
Authors: Pieter Wuytens, Hans Demol, Nina Turk, Andre Skirtach, Mohamed Lamkanfi, Roel Baets
Pages: 345 - 361 - Carboxylate isosteres for caspase inhibitors : the acylsulfonamide case revisited(2017)
Authors: Y Adriaenssens, Daniel Jiménez Fernandez, F Elvas, J Joossens, A Lambeir, K Augustyns, Mohamed Lamkanfi, P Van der Veken
Pages: 7456 - 7473 - The inflammasome turns 15(2017)
Authors: Mohamed Lamkanfi, Vishva M Dixit
Pages: 534 - 535 - Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection(2016)
Authors: Xiaopeng Qi, Si Ming Man, RK Subbarao Malireddi, Rajendra Karki, Christopher Lupfer, Prajwal Gurung, Geoffrey Neale, Clifford S Guy, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 2081 - 2097
Patents
1 - 1 of 1
- Label free detection of protease activity (Inventor)