Researcher
Mohamed Lamkanfi
- Keywords:Cell death and inflammation
- Disciplines:Immunology not elsewhere classified, Cell signalling, Applied immunology, Innate immunity, Autoimmunity, Immunogenetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2015 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From5 Aug 2009 → 30 Sep 2015 - Research Department (Administrative office)
Member
From1 Jul 2005 → 30 Jun 2006 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2000 → 30 Sep 2004
Projects
1 - 10 of 28
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- A MESO QuickPlex SQ system to measure single or multiple immunotargets in biofluidsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Targeting NLRP3-mediated inflammation with novel chemotypesFrom1 Oct 2022 → TodayFunding: Horizon Europe - European Research Council (ERC)
- Cell Death Regulation and Role in Infection and Inflammatory DiseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Single cell analysis of inflammasome-mediated IL-1ß secretion in primary human monocytesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Regulation of the Nlrp1a inflammasome in cutaneous and systemic autoinflammationFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Mechanisms and regulation of inflammasome-associated programmed cell deathFrom1 Jan 2020 → 31 Dec 2021Funding: H2020 - Frontier Research (ERC)
- Investigating microglia inflammasome activation and regulation in
Alzheimer diseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research Grant
Publications
111 - 120 of 131
- IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation(2010)
Authors: Mohammad Hasan Zaki, Peter Vogel, Mathilde Body-Malapel, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 4912 - 4920 - Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes(2010)
Authors: RK Subbarao Malireddi, Sirish Ippagunta, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 3127 - 3130 - Manipulation of host cell death pathways during microbial infections(2010)
Authors: Mohamed Lamkanfi, Vishva M Dixit
Pages: 44 - 54 - Nlrp3: an immune sensor of cellular stress and infection(2010)
Authors: Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 792 - 795 - Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis(2010)
Authors: Sirish K Ippagunta, David D Brand, JiWen Luo, Kelli L Boyd, Christopher Calabrese, Rinke Stienstra, Frank L Van de Veerdonk, Mihai G Netea, Leo AB Joosten, Mohamed Lamkanfi, et al.
Pages: 12454 - 12462 - The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis(2010)
Authors: Md Hasan Zaki, Kelli L Boyd, Peter Vogel, Michael B Kastan, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 379 - 391 - The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal(2010)
Authors: Ellen Wirawan, Mohamed Lamkanfi, Nele Festjens, Jelle Verspurten, Tom Vanden Berghe, Peter Vandenabeele
Pages: 421 - 433 - Caspase-7: a protease involved in apoptosis and inflammation(2010)
Authors: Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Pages: 21 - 24 - Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella(2010)
Authors: Petr Broz, Kim Newton, Mohamed Lamkanfi, Sanjeev Mariathasan, Vishva M Dixit, Denise M Monack
Pages: 1745 - 1755 - Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia(2010)
Authors: Mohamed Lamkanfi, Anasuya Sarkar, Alberto C Vitari, mal AO Amer, Mark D Wewers, Kevin J Tracey, Thirumala-Devi Kanneganti, Vishva M Dixit
Pages: 4385 - 4392
Patents
1 - 1 of 1
- Label free detection of protease activity (Inventor)