Researcher
Mohamed Lamkanfi
- Keywords:Cell death and inflammation
- Disciplines:Immunology not elsewhere classified, Cell signalling, Applied immunology, Innate immunity, Autoimmunity, Immunogenetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2015 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From5 Aug 2009 → 30 Sep 2015 - Research Department (Administrative office)
Member
From1 Jul 2005 → 30 Jun 2006 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2000 → 30 Sep 2004
Projects
1 - 10 of 28
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- A MESO QuickPlex SQ system to measure single or multiple immunotargets in biofluidsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Targeting NLRP3-mediated inflammation with novel chemotypesFrom1 Oct 2022 → 31 Mar 2024Funding: Horizon Europe - European Research Council (ERC)
- Cell Death Regulation and Role in Infection and Inflammatory DiseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Single cell analysis of inflammasome-mediated IL-1ß secretion in primary human monocytesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Regulation of the Nlrp1a inflammasome in cutaneous and systemic autoinflammationFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Mechanisms and regulation of inflammasome-associated programmed cell deathFrom1 Jan 2020 → 31 Dec 2021Funding: H2020 - Frontier Research (ERC)
- Investigating microglia inflammasome activation and regulation in
Alzheimer diseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research Grant
Publications
11 - 20 of 131
- Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax(2022)
Authors: Filip Van Hauwermeiren, Nina Van Opdenbosch, Hanne Van Gorp, Nathalia de Vasconcelos, Geert van Loo, Peter Vandenabeele, Thirumala-Devi Kanneganti, Mohamed Lamkanfi
- Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa(2022)
Authors: Karin Santoni, David Pericat, Leana Gorse, Julien Buyck, Miriam Pinilla, Laure Prouvensier, Salimata Bagayoko, Audrey Hessel, Stephen Adonai Leon-Icaza, Elisabeth Bellard, et al.
- GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis(2022)
Authors: Dhruv Chauhan, Dieter Demon, Lieselotte Vande Walle, Oonagh Paerewijck, Annalisa Zecchin, Leslie Bosseler, Karin Santoni, Remi Planes, Sílvia Ribó Gené, Amelie Fossoul, et al.
- Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice(2021)
Authors: Oceane Dufies, Anne Doye, Johan Courjon, Cedric Torre, Gregory Michel, Celine Loubatier, Arnaud Jacquel, Paul Chaintreuil, Alissa Majoor, Rodolphe R. Guinamard, et al.
Pages: 401 - 412 - Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger(2021)
Authors: Aranit Harizaj, Filip Van Hauwermeiren, Stephan Stremersch, Herlinde De Keersmaecker, Toon Brans, Juan Fraire, Karolien Grauwen, Ine Lentacker, Mohamed Lamkanfi, Kevin Braeckmans
Pages: 6592 - 6604 - IL1 beta promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D(2021)
Authors: Mate Kiss, Pedro Henrique Viana Saavedra, Els Lebegge, Helena Van Damme, Aleksandar Murgaski, Junbin Qian, Manuel Ehling, Samantha Pretto, Evangelia Bolli, Jiri Keirsse, et al.
Pages: 309 - 323 - Familial mediterranean fever and COVID-19 : friends or foes?(2020)
Authors: Alessandro Stella, Mohamed Lamkanfi, Piero Portincasa
- Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities(2020)
Authors: Arne Martens, Dario Priem, Esther Hoste, Leen Catrysse, Sofie Voet, Mozes Sze, Hanna-Kaisa Vikkula, Karolina Slowicka, Tino Hochepied, Kalliopi Iliaki, et al.
Pages: 381 - 387 - Snapshot of a deadly embrace : the caspase-1-GSDMD interface(2020)
Authors: Mohamed Lamkanfi
Pages: 6 - 8 - Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever(2020)
Authors: Hanne Van Gorp, Linyan Huang, Pedro Henrique Viana Saavedra, Marnik Vuylsteke, Tomoko Asaoka, Giusi Prencipe, Antonella Insalaco, Benson Ogunjimi, Jerold Jeyaratnam, Ilaria Cataldo, et al.
Pages: 960 - 968
Patents
1 - 1 of 1
- Label free detection of protease activity (Inventor)