Researcher
Mohamed Lamkanfi
- Keywords:Cell death and inflammation
- Disciplines:Immunology not elsewhere classified, Cell signalling, Applied immunology, Innate immunity, Autoimmunity, Immunogenetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2015 → 30 Sep 2018 - Department of Biochemistry (Department)
Member
From5 Aug 2009 → 30 Sep 2015 - Research Department (Administrative office)
Member
From1 Jul 2005 → 30 Jun 2006 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2000 → 30 Sep 2004
Projects
1 - 10 of 28
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- A MESO QuickPlex SQ system to measure single or multiple immunotargets in biofluidsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Targeting NLRP3-mediated inflammation with novel chemotypesFrom1 Oct 2022 → 31 Mar 2024Funding: Horizon Europe - European Research Council (ERC)
- Cell Death Regulation and Role in Infection and Inflammatory DiseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Single cell analysis of inflammasome-mediated IL-1ß secretion in primary human monocytesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Regulation of the Nlrp1a inflammasome in cutaneous and systemic autoinflammationFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Mechanisms and regulation of inflammasome-associated programmed cell deathFrom1 Jan 2020 → 31 Dec 2021Funding: H2020 - Frontier Research (ERC)
- Investigating microglia inflammasome activation and regulation in
Alzheimer diseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 131
- Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease(2024)
Authors: Sahana Srinivasan, Daliya Kancheva, Sofie De Ren, Takashi Saito, Maude Jans, Fleur Boone, Charysse Vandendriessche, Ine Paesmans, Herve Maurin, Roosmarijn Vandenbroucke, et al.
- Drugging the NLRP3 inflammasome : from signalling mechanisms to therapeutic targets(2024)
Authors: Lieselotte Vande Walle, Mohamed Lamkanfi
Pages: 43 - 66 - Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice(2023)
Authors: Karel Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Inge Bruggeman, Amelie Fossoul, Jozefien Declercq, Helena Catharine Aegerter, Andy Wullaert, et al.
- The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice(2023)
Authors: Elien Eeckhout, Tomoko Asaoka, Hanne Van Gorp, Dieter Demon, Charlotte Girard-Guyonvarc'h, Vanessa Andries, Lars Vereecke, Cem Gabay, Mohamed Lamkanfi, Geert van Loo, et al.
- Tuberculosis : the tug of war between pathogen and inflammasome(2023)
Authors: Filip Van Hauwermeiren, Mohamed Lamkanfi
Pages: R33 - R36 - Comment on : effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3(2023)
Authors: Lieselotte Vande Walle, Mohamed Lamkanfi
Pages: E166 - E167 - Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever(2023)
Authors: Selina K. Jorch, Annika McNally, Philipp Berger, Jonas Wolf, Kim Kaiser, Andrian Chetrusca Covash, Stefanie Robeck, Isabell Pastau, Olesja Fehler, Saskia-L. Jauch-Speer, et al.
Pages: 230 - 243 - The human inflammasomes(2022)
Authors: Oonagh Paerewijck, Mohamed Lamkanfi
- How to dodge pyroptosis : lessons from Shigella flexneri(2022)
Authors: Filip Van Hauwermeiren, Mohamed Lamkanfi
Pages: 227 - 228 - Nonredundancy of IL-1 alpha and IL-1 beta is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection(2022)
Authors: Kevin Eislmayr, Annika Bestehorn, Luisa Morelli, Martina Borroni, Lieselotte Vande Walle, Mohamed Lamkanfi, Pavel Kovarik
Patents
1 - 1 of 1
- Label free detection of protease activity (Inventor)