Researcher
Mieke Geens
- Keywords:Medicine
- Disciplines:Genetics, Epigenetics, Stem cell biology
Affiliations
- Reproduction and Genetics (Research group)
Member
From21 Jun 2010 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → 30 Sep 2021 - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → 31 Dec 2020 - Faculty of Medicine and Pharmacy (Faculty)
Member
From22 Jun 2017 → 7 Sep 2017 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 30 Sep 2021 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 6 Jun 2019 - Department of Embryology and Genetics (Department)
Member
From1 Mar 2013 → 31 Dec 2013 - Department of Embryology and Genetics (Department)
Member
From1 Oct 2005 → 31 Dec 2013 - Biology of the Testis (Research group)
Member
From1 Oct 2005 → 30 Sep 2010
Projects
1 - 5 of 5
- The identification of copy number variations that impede differentiation of human pluripotent stem cells.From1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- FWO-SB-Scholarship: defining the molecular basis for liver cell differentiation deficiency in human pluripotent stem cellsFrom1 Jan 2017 → 31 Dec 2020Funding: FWO fellowships
- Identification of molecular regulators of differentiation potential in human embryonic stem cells.From1 Oct 2015 → 30 Sep 2019Funding: FWO fellowships
- Totipotency versus fate in human embryonic stem cellsFrom1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- (In)stability of X chromosome inactivation in human pluripotent stem cellsFrom1 Jan 2012 → 31 Dec 2012Funding: FWO research grant KAN
Publications
1 - 10 of 28
- Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm(2021)
Authors: Christina Markouli, Edouard Couvreu De Deckersberg, Dominika Dziedzicka, Marius Regin, Silvie Franck, Alexander Scott Keller, Alexander Gheldof, Mieke Geens, Karen Sermon, C Spits
- Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm(2021)
Authors: Dominika Dziedzicka, Mukul Tewary, Alexander Scott Keller, Laurentijn Tilleman, Laura Prochazka, Joel Östblom, Edouard Couvreu De Deckersberg, Christina Markouli, Silvie Franck, Filip Van Nieuwerburgh, et al.
- Differentiation propensity of human embryonic stem cell lines: assays and molecular mechanisms.(2020)
Authors: Dominika Dziedzicka, Mieke Geens, Karen Sermon
- Uncovering low-level mosaicism in human embryonic stem cells using high throughput single cell shallow sequencing(2019)
Authors: Alexander Scott Keller, Laurentijn Tilleman, Dominika Dziedzicka, Filippo Zambelli, Karen Sermon, Filip Van Nieuwerburgh, C Spits, Mieke Geens
- High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning(2019)
Authors: Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, et al.
- Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.(2019)
Authors: Christina Markouli, Edouard Couvreu De Deckersberg, Marius Regin, Ha Nguyen Thi, Filippo Zambelli, Alexander Scott Keller, Dominika Dziedzicka, Joery De Kock, Laurentijn Tilleman, Filip Van Nieuwerburgh, et al.
Pages: 163-176 - Losing Pluripotency. The impact of genomic alterations on differentiation.(2019)
Authors: Christina Markouli, Mieke Geens, Claudia Spits
- Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells(2018)
Authors: Filippo Zambelli, Joke Mertens, Dominika Dziedzicka, Johan Sterckx, Christina Markouli, Alexander Scott Keller, Philippe Tropel, Laura Jung, Stephane Viville, Hilde Van De Velde, et al.
Pages: 102-114 - The role of the reprogramming method and pluripotency state in gamete differentiation from patient-specific human pluripotent stem cells(2018)
Authors: Sanghamitra Mishra, Ela Kaçin, P Stamatiadis, Silvie Franck, M Van der Jeught, Heidi Mertes, Guido Pennings, Philippe De Sutter, Karen Sermon, Björn Heindryckx, et al.
Pages: 173-184 - Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells(2018)
Authors: Alexander Scott Keller, Dominika Dziedzicka, Filippo Zambelli, Christina Markouli, Karen Sermon, C Spits, Mieke Geens
Pages: 162–175