Researcher
Michelle De bruyn
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal chemistry, Medicinal products, Pharmaceutical analysis and quality assurance, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Other medical and health sciences
Affiliations
- Medical Biochemistry (Research group)
Member
From1 Oct 2021 → 30 Sep 2023 - Medical Biochemistry (Research group)
Member
From15 Oct 2017 → 30 Sep 2021
Publications
1 - 8 of 8
- Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases(2023)
Authors: Alba Ramos Llorca, Lisse Decraecker, Valerie Cacheux, Irena Zeiburlina, Michelle De bruyn, Louise Battut, Carlos Moreno Cinos, Davide Ceradini, Eric Espinosa, Gilles Dietrich, et al.
Pages: 1 - 17 - Activation of the carboxypeptidase U (CPU, TAFIa, CPB2) system in patients with SARS-CoV-2 infection could contribute to COVID-19 hypofibrinolytic state and disease severity prognosis(2022)
Authors: Karen Claesen, Yani Sim, An Bracke, Michelle De bruyn, Emilie De Hert, Gwendolyn Vliegen, An Hotterbeekx, Alexandra Vujkovic, Lida van Petersen, Fien De Winter, et al.
Pages: 1 - 11 - The effect of serine protease inhibitors on visceral pain in different rodent models with an intestinal insult(2022)
Authors: Hannah Ceuleers, Nikita Hanning, Michelle De bruyn, Joris De Man, Heiko De Schepper, Qian Li, Liansheng Liu, Steven Abrams, Annemieke Smet, Jurgen Joossens, et al.
Pages: 1 - 17 - Profiling of proteases as potential therapeutic targets(2022)
Authors: Michelle De bruyn, Ingrid De Meester, Benedicte De Winter
Number of pages: 259 - Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patients(2022)
Authors: An Bracke, Emilie De Hert, Michelle De bruyn, Karen Claesen, Gwendolyn Vliegen, Alexandra Vujkovic, Lida van Petersen, Fien De Winter, An Hotterbeekx, Isabel Brosius, et al.
Pages: 4 - 11 - Local colonic administration of a serine protease inhibitor improves post-inflammatory visceral hypersensitivity in rats(2021)
Authors: Nikita Hanning, Michelle De bruyn, Hannah Ceuleers, Tim Boogaerts, Maya Berg, Annemieke Smet, Heiko De Schepper, Jurgen Joossens, Alexander van Nuijs, Joris De Man, et al.
- Proteolytic cleavage of bioactive peptides and protease-activated receptors in acute and post-colitis(2021)
Authors: Michelle De bruyn, Hannah Ceuleers, Nikita Hanning, Maya Berg, Joris De Man, Paco Hulpiau, Cedric Hermans, Ulf-Hakan Stenman, Hannu Koistinen, Benedicte De Winter, et al.
- Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome(2018)
Authors: Hannah Ceuleers, Nikita Hanning, Leen Heirbaut, Samuel Van Remoortel, Jurgen Joossens, Pieter Van Der Veken, Sven Francque, Michelle De bruyn, Joris De Man, Jean-Pierre Timmermans, et al.
Pages: 3516 - 3533