Researcher
Melissa SCHEPERS
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Autoimmunity, Behavioural neuroscience, Cognitive neuroscience, Neurological and neuromuscular diseases
Affiliations
- Neurosciences (Department)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Member
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Member
From15 Jul 2017 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From15 Jul 2017 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From15 Jul 2017 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From15 Jul 2017 → 31 Dec 2019
Projects
1 - 4 of 4
- Supporting the oligodendrocyte-neuron coupling: pulling back to curtain on downstream PDE4D signallingFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Targeting phosphodiesterase 4D (PDE4D) isoforms, a novel approach to boost repair in multiple sclerosisFrom1 Feb 2021 → 31 May 2023Funding: FWO Strategic Basic Research Grant
- Targeting enzymes on the splice variants level, a novel approach to boost repair in multiple sclerosisFrom1 Feb 2019 → 31 Jan 2021Funding: FWO Strategic Basic Research Grant
- Relieving the epigenetic blockade in progressive multiple sclerosis – making repair possible againFrom17 Jan 2019 → 31 Dec 2019Funding: Nonprofit institution or equivalents
Publications
1 - 10 of 41
- Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination(2024)
Authors: Melissa SCHEPERS, Tim VANMIERLO
Pages: 493 - 494 - The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation(2024)
Authors: Emily WILLEMS, Melissa SCHEPERS, Elisabeth PICCART, Esther WOLFS, Niels HELLINGS, Maria Ait-Tihyaty, Tim VANMIERLO
- Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury(2023)
Authors: Femke Mussen, Jana VAN BROECKHOVEN, Niels HELLINGS, Melissa SCHEPERS, Tim VANMIERLO
- Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?(2023)
Authors: Ellis NELISSEN, Melissa SCHEPERS, Laura PONSAERTS, Sebastien Foulquier, Annelies BRONCKAERS, Tim VANMIERLO, Peter Sandner, Jos Prickaerts
- From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Assia TIANE, Melissa SCHEPERS, Rick A. Reijnders, Lieve VAN VEGGEL, Sarah CHENINE, Ben ROMBAUT, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Gruenewald, et al.
Pages: 283 - 299 - Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function(2023)
Authors: Baharak HOSSEINKHANI, Gayel DURAN, Cindy HOEKS, Doryssa HERMANS, Melissa SCHEPERS, Paulien BAETEN, Joren POELMANS, Britt Coenen, Kuebra Bekar, Isabel Pintelon, et al.
- Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology(2023)
Authors: Dean PAES, Melissa SCHEPERS, Emily WILLEMS, Ben ROMBAUT, Assia TIANE, Yevgeniya Solomina, Amy Tibbo, Connor Blair, Elka Kyurkchieva, George S. Baillie, et al.
- Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice(2023)
Authors: Philippos KOULOUSAKIS, Emily WILLEMS, Melissa SCHEPERS, Ben ROMBAUT, Jos Prickaerts, Tim VANMIERLO, Daniel van den Hove
Pages: 1207 - 1219 - Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis(2023)
Authors: Melissa SCHEPERS, Dean PAES, Assia TIANE, Ben ROMBAUT, Elisabeth PICCART, Lieve VAN VEGGEL, Pascal GERVOIS, Chiara Brullo, Olga Bruno, Ernesto Fedele, et al.
Pages: 1 - 22 - Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model(2023)
Authors: Melissa SCHEPERS, Afonso Malheiro, Adrian Seijas Gamardo, Niels HELLINGS, Jos Prickaerts, Lorenzo Moroni, Tim VANMIERLO, Paul Wieringa