Researcher
Matthias Trappeniers
- Disciplines:Medicinal products, Pharmacognosy and phytochemistry, Pharmaceutics, Biomarker discovery and evaluation, Other pharmaceutical sciences, Drug discovery and development, Toxicology and toxinology, Pharmacotherapy, Pharmacology
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2006 → 30 Sep 2010
Projects
1 - 1 of 1
- Development of KRN 7000 analogues with an improvement selectivity profileFrom1 Oct 2007 → 30 Sep 2010Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 10 of 10
- Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis(2011)
Authors: Sandrine Aspeslagh, Yali Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girard, Tine Decruy, Michael Drennan, Luc Leybaert, Jing Wang, et al.
Pages: 2294 - 2305 - Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo(2011)Volume: 70
Authors: Sandrine Aspeslagh, YaLi Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girardi, Tine Decruy, Katrien Van Beneden, Koen Venken, Michael Drennan, et al.
Pages: A53 - A53 - 6''-Modified alpha-GalCer analogs capable of establishing an extra interaction with Cd1d leading to a polarized Th1 response and superior tumor protection(2011)Volume: 241
Authors: Serge Van Calenbergh, Nora Pauwels, Sandrine Aspeslagh, YaLi Li, Matthias Trappeniers, Dirk Zajonc, Dirk Elewaut
Number of pages: 1 - Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid(2010)Volume: 135
Authors: Sandrine Aspeslagh, Yali Li, Tine Decruy, Katrien Van Beneden, Koen Venken, Matthias Trappeniers, Serge Van Calenbergh, Dirk Zajonc, Dirk Elewaut
Pages: S40 - S40 - Synthesis and evaluation of amino-modified U+03B1-GalCer analogues(2010)
Authors: Matthias Trappeniers, René Chofor, Sandrine Aspeslagh, Yali Li, Bruno Linclau, Dirk M Zajonc
Pages: 2928 - 2931 - Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid(2010)Volume: 135
Authors: Sandrine Aspeslagh, Yali Li, Tine Decruy, Katrien Van Beneden, Michael Drennan, Koen Venken, Matthias Trappeniers, Serge Van Calenbergh, Dirk Zajonc, Dirk Elewaut
Pages: S13 - S14 - The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000(2009)
Authors: Leo Leung, Cyrille Tomassi, Tine Decruy, Matthias Trappeniers, Yifang Gao, Tim Elliott, Aymen Al-Shamkhani, Christian Ottensmeier, Joern M. Werner, Anthony Williams, et al.
Pages: 329 - 334 - Synthesis and in vitro evaluation of U+03B1-GalCer epimers(2008)
Authors: Matthias Trappeniers, Stijn Goormans, Tine Decruy, Bruno Linclau, Aymen Al-Shamkhani, Tim Elliott, Christian Ottensmeier, Joern M. Werner
Pages: 1061 - 1070 - 6'-Derivatised U+03B1-GalCer analogues capable of inducing strong CD1d-mediated Th1-biased NKT cell responses in mice(2008)
Authors: Matthias Trappeniers, Tine Decruy, Bruno Linclau
Pages: 16468 - 16469 - Synthesis of sphingosine- and sugar modified α-GalCer analogues : towards new immunomodulatory agents
Authors: Matthias Trappeniers