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Researcher
Matthew Holt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Other biological sciences
- See also: Matthew Holt (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Glia Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → 31 Jan 2022 - Holt Lab (Research group)
Responsible
From1 Jan 2017 → 31 Jan 2022 - Department of Human Genetics (Department)
Member
From1 Oct 2011 → 31 Dec 2016
Projects
1 - 10 of 34
- Astrocytes dysfunctions in Phelan McDermid syndrome: from mechanisms towards new therapeutic strategiesFrom1 May 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The astrocyte-specific proteome in inhibitory tripartite synapse formation and function in the context of Autism Spectrum DisorderFrom11 Jan 2022 → TodayFunding: FWO fellowships
- Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The role of astrocytes (sub)types in adult brain plasticityFrom19 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Elucidating the role of astrocytes in noradrenaline-mediated seizure suppression and its possible therapeutic relevance for Alzheimer's disease.From1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Critical periods and brain plasticity – astrocytes as key modulators of cortical wiringFrom16 Aug 2021 → 8 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the contribution of astrocytes to experience-dependent cortical plasticity.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Connecting polyamine transport in astrocytes to neurodevelopmental disorders via ATP13A4From1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
- Cell subtype-specific neuron-glia contributions to cortical plasticityFrom1 Oct 2020 → TodayFunding: BOF - projects
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
31 - 40 of 45
- Developing 3D SEM in a broad biological context(2015)
Authors: Matthew Holt, Stefan Janssens, Michal Slezak
Pages: 80 - 96 - Differential centrifugation-based biochemical fractionation of the Drosophila adult CNS(2014)
Authors: Matthew Holt
Pages: 2796 - 808 - Drep-2 is a novel synaptic protein important for learning and memory(2014)
Authors: Matthew Holt
- Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton(2014)
Authors: Nick Smisdom, Matthew Holt
Pages: 13445 - 60 - The astrocyte marker Aldh1L1 does not reliably label enteric glial cells(2014)
Authors: Werend Boesmans, Matthew Holt, Pieter Vanden Berghe
Pages: 102 - 105 - Small-scale isolation of synaptic vesicles from mammalian brain(2013)
Authors: Matthew Holt
Pages: 998 - 1009 - Rapid Fusion of Synaptic Vesicles with Reconstituted Target SNARE Membranes(2013)
Authors: Matthew Holt
Pages: 1950 - 1958 - LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis(2012)
Authors: Samer Matta, Wim Mandemakers, Vanessa Morais, Sven Vilain, Dominik Haddad, Lucia Chavez Gutierrez, Eric Karran, Matthew Holt, Bart De Strooper, Patrik Verstreken
Pages: 1008 - 1021 - LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis(2012)
Authors: Samer Matta, Kristof Van Kolen, Raquel da Cunha, Geert van den Bogaart, Wim Mandemakers, Katarzyna Miskiewicz, Pieter-Jan De Bock, Vanessa Morais, Sven Vilain, Dominik Haddad, et al.
Pages: 1008 - 1021 - Coupling exo- and endocytosis: An essential role for PIP2 at the synapse(2012)
Authors: Marta Koch, Matthew Holt
Pages: 1114 - 1132
Patents
1 - 2 of 2
- Novel method (Inventor)
- Novel method (Inventor)