< Back to previous page
Researcher
Matthew Holt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Other biological sciences
- See also: Matthew Holt (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Glia Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → 31 Jan 2022 - Holt Lab (Research group)
Responsible
From1 Jan 2017 → 31 Jan 2022 - Department of Human Genetics (Department)
Member
From1 Oct 2011 → 31 Dec 2016
Projects
1 - 10 of 34
- Astrocytes dysfunctions in Phelan McDermid syndrome: from mechanisms towards new therapeutic strategiesFrom1 May 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The astrocyte-specific proteome in inhibitory tripartite synapse formation and function in the context of Autism Spectrum DisorderFrom11 Jan 2022 → TodayFunding: FWO fellowships
- Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The role of astrocytes (sub)types in adult brain plasticityFrom19 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Elucidating the role of astrocytes in noradrenaline-mediated seizure suppression and its possible therapeutic relevance for Alzheimer's disease.From1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Critical periods and brain plasticity – astrocytes as key modulators of cortical wiringFrom16 Aug 2021 → 8 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the contribution of astrocytes to experience-dependent cortical plasticity.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Connecting polyamine transport in astrocytes to neurodevelopmental disorders via ATP13A4From1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
- Cell subtype-specific neuron-glia contributions to cortical plasticityFrom1 Oct 2020 → TodayFunding: BOF - projects
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
21 - 30 of 45
- Astrocyte VGLUTs are involved in the control of kainate-induced epileptic seizures(2019)
Authors: Matthew Holt
Pages: E760 - E760 - Production, Purification, and Quality Control for Adeno-associated Virus-based Vectors(2019)
Authors: Catherine Marneffe, Marika Marino, Matthew Holt
- Widespread transduction of astrocytes and neurons in the mouse central nervous system after systemic delivery of a self-complementary AAV-PHP.B vector(2018)
Authors: Filip de Vin, Stephanie Castaldo, Matthew Holt
Pages: 83 - 92 - A Fat-Facets-Dscaml-JNK Pathway Enhances Axonal Growth in Development and after Injury(2018)
Authors: Natalie De Geest, Matthew Holt, Dietmar Schmucker, Bassem Hassan
- Satnav for cells: Destination membrane fusion(2017)
Authors: Matthew Holt
Pages: 14 - 23 - Tau association with synaptic vesicles causes presynaptic dysfunction(2017)
Authors: Lujia Zhou, Joseph McInnes, Matthew Holt, Yu-Chun Wang, Sven Vilain, Bart De Strooper, Joris de Wit, Patrik Verstreken
Pages: 15295 - An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody(2017)
Authors: Mykhailo Batiuk, Filip de Vin, Chen Li, Mark Fiers, Matthew Holt
Pages: 8874 - 8891 - The oxygen sensor PHD2 controls dendritic spines and synapses via modification of filamin A(2016)
Authors: Christian Lange, Guy Eelen, Matthew Holt, Dirk Daelemans, Bart Ghesquière, Mieke Dewerchin, Peter Carmeliet
Pages: 2653 - 67 - Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function(2015)
Authors: Matthew Holt
Pages: 8362 - Development and validation of flexible system for selective genetic manipulation of astrocytes in wild-type mouse(2015)
Authors: Filip de Vin, Matthew Holt
Pages: E200 - E200
Patents
1 - 2 of 2
- Novel method (Inventor)
- Novel method (Inventor)