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Researcher
Matthew Holt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Other biological sciences
- See also: Matthew Holt (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Glia Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → 31 Jan 2022 - Holt Lab (Research group)
Responsible
From1 Jan 2017 → 31 Jan 2022 - Department of Human Genetics (Department)
Member
From1 Oct 2011 → 31 Dec 2016
Projects
1 - 10 of 34
- Astrocytes dysfunctions in Phelan McDermid syndrome: from mechanisms towards new therapeutic strategiesFrom1 May 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The astrocyte-specific proteome in inhibitory tripartite synapse formation and function in the context of Autism Spectrum DisorderFrom11 Jan 2022 → TodayFunding: FWO fellowships
- Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The role of astrocytes (sub)types in adult brain plasticityFrom19 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Elucidating the role of astrocytes in noradrenaline-mediated seizure suppression and its possible therapeutic relevance for Alzheimer's disease.From1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Critical periods and brain plasticity – astrocytes as key modulators of cortical wiringFrom16 Aug 2021 → 8 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the contribution of astrocytes to experience-dependent cortical plasticity.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Connecting polyamine transport in astrocytes to neurodevelopmental disorders via ATP13A4From1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
- Cell subtype-specific neuron-glia contributions to cortical plasticityFrom1 Oct 2020 → TodayFunding: BOF - projects
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
11 - 20 of 45
- Reactive astrocyte nomenclature, definitions, and future directions(2021)
Authors: Bart De Strooper, Matthew Holt
Pages: 312 - 325 - Astrocytes, Noradrenaline, α1-Adrenoreceptors, and Neuromodulation: Evidence and Unanswered Questions(2021)
Authors: Jérôme Wahis, Matthew Holt
- The projection specific logic to sampling imputs by the superior colliculus(2021)
Authors: Chen Li, Karl Farrow, Matthew Holt
- Profiling protoplasmic astrocytes as the missing cellular component in experience-dependent visual cortex plasticity(2020)
Authors: Maroussia Hennes, Lut Arckens, Matthew Holt
- Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease(2020)
Authors: Dries T'Syen, Tom Theys, Matthew Holt, Bart De Strooper
- Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map(2020)
Authors: Araks Martirosyan, Matthew Holt
Pages: 500 - + - Astrocytes shape the plastic response of adult cortical neurons to vision loss(2020)
Authors: Maroussia Hennes, Nathalie Lombaert, Jérôme Wahis, Chris Van den Haute, Matthew Holt, Lut Arckens
Pages: 2102 - 2118 - Identification of region-specific astrocyte subtypes at single cell resolution(2020)
Authors: Araks Martirosyan, Jérôme Wahis, Filip de Vin, Catherine Marneffe, Thierry Voet, Matthew Holt
- No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience(2020)
Authors: Francisco Pestana, Araks Martirosyan, Matthew Holt
- Distinct Mechanisms for Visual and Motor-Related Astrocyte Responses in Mouse Visual Cortex(2019)
Authors: Paul P Van Veldhoven, Chris Van den Haute, Vincent Bonin, Matthew Holt
Pages: 1 - 8
Patents
1 - 2 of 2
- Novel method (Inventor)
- Novel method (Inventor)