Researcher
Mathy Froeyen
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Department of Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Oct 2010 → 30 Sep 2011 - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Jul 2001 → Today - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Jun 2001
Projects
1 - 10 of 11
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- Exploring the Sequence and Functional Landscapes of Natural and Engineered PolymerasesFrom8 Oct 2018 → TodayFunding: FWO fellowships
- Drug design strategies against newly emerging viral diseasesFrom17 Oct 2016 → 30 Oct 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigations on base pairing between N8-glycosylated 8-aza-guanine bases and 8-substituted purine bases.From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Development of XNA ligases as tools for synthetic biologyFrom22 Sep 2015 → 17 Oct 2019Funding: BOF - doctoral mandates, BOF - Doctoral projects
- Development of a xenozyme and an XNA ligase.From1 Oct 2014 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- Rational Design of XNA Processing EnzymesFrom22 Sep 2014 → 6 Oct 2020Funding: BOF - Doctoral projects
- Synthesis of modified nucleotides for application in medicine and biotechnology.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 112
- Family wide analysis of aminoacyl-sulfamoyl-3-deaza-adenosine analogues as inhibitors of aminoacyl-tRNA synthetases(2018)
Authors: Baole Zhang, Steff De Graef, Manesh Nautiyal, Luping Pang, Bharat Gadakh, Mathy Froeyen, Lieve Vanmellaert, Sergei Strelkov, Stephen Weeks, Arthur Van Aerschot
Pages: 384 - 396 - Molecular docking study on the interaction between 2-substituted-4,5-difuryl Imidazoles with different protein target for antileishmanial activity(2018)
Authors: Mathy Froeyen
Pages: 14 - 22 - New class of early-stage enterovirus inhibitors with a novel mechanism of action(2017)
Authors: Yipeng Ma, Rana Abdelnabi, Leen Delang, Mathy Froeyen, Walter Luyten, Johan Neyts, Carmen Mirabelli
Pages: 67 - 74 - Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents (vol 24, pg 5172, 2016)(2017)
Authors: Lijun Song, Martijn DP Risseeuw, Mathy Froeyen, Izet Karalic, Jan Goeman, Davie Cappoen, Johan Van der Eycken, Paul Cos, Helene Munier-Lehmann, Serge Van Calenbergh
Pages: 5889 - 5889 - Molecular Dynamics of Double Stranded Xylo-Nucleic Acid(2017)
Authors: Daryna Smyrnova, Mathy Froeyen, Piet Herdewyn, Arnout Ceulemans
Pages: 5028 - 5038 - Understanding the mechanism of the broad-spectrum antiviral activity of favipiravir (T-705): key role of the F1 motif of the viral polymerase(2017)
Authors: Rana Abdelnabi, Pieter Leyssen, Mathy Froeyen, Johan Neyts, Leen Delang
- Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors(2017)
Authors: Suzanne Kaptein, Johan Neyts, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Pages: 101 - 109 - Structural properties and mechanical stability of monoclinic lithium disilicate(2017)
Authors: Yohandys Alexis Zulueta Leyva, Mathy Froeyen, Minh Nguyen
- Structural properties and mechanical stability of lithium-ion based materials. A theoretical study(2017)
Authors: Yohandys Alexis Zulueta Leyva, Mathy Froeyen, Minh Nguyen
Pages: 271 - 279 - Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers(2017)
Authors: Koen Vermeulen, Mathy Froeyen, Guy Bormans
Pages: 787 - 797