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Researcher
Martijn Kerkhofs
- Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From1 Jul 2015 → Today
Projects
1 - 2 of 2
- Phosphorylation status of GRP75 and its impact on MAMs dynamics and functionFrom1 Jan 2021 → 31 Oct 2021Funding: BOF - postdoctoral mandates
- Insights in pathophysiological changes connected to BcI-2-dependence at the endoplasmic recticulum in diffuse large B-cell lymphomas.From1 Oct 2016 → 11 Dec 2020Funding: FWO fellowships
Publications
1 - 10 of 27
- Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells(2023)
Authors: Flore Sneyers, Martijn Kerkhofs, Rita La Rovere, Mieke Dewerchin, Geert Bultynck
- The ER-mitochondria interface, where Ca2+and cell death meet(2023)
Authors: Martijn Kerkhofs, Jens Loncke, Geert Bultynck, Jan Parys
- The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca2+ stores in cellulo(2022)
Authors: Martijn Kerkhofs, Peter Vangheluwe, Geert Bultynck, Tim Vervliet
- A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca2+ signalling through IP3 receptors(2022)
Authors: Martijn Kerkhofs, Geert Bultynck, Jan Parys
- Dynamic control of mitochondria-associated membranes by kinases and phosphatases in health and disease(2021)
Authors: Flore Sneyers, Geert Bultynck, Martijn Kerkhofs
Pages: 6541 - 6556 - Getting old without type 2 IP3 receptors(2021)
Authors: Martijn Kerkhofs, Geert Bultynck
- Bok joining the "Ca2+ club"(2021)
Authors: Nicolas Rosa, Martijn Kerkhofs, Geert Bultynck
- Balancing ER-Mitochondrial Ca2+Fluxes in Health and Disease(2021)
Authors: Jens Loncke, Jan Parys, Martijn Kerkhofs, Geert Bultynck
Pages: 598 - 612 - Cancer cell death strategies by targeting Bcl-2's BH4 domain(2021)
Authors: Martijn Kerkhofs, Wim Dehaen, Geert Bultynck
- BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening(2021)
Authors: Martijn Kerkhofs, Rita La Rovere, Ann Janssens, Peter Vandenberghe, Jan Parys, Geert Bultynck