Researcher
Marlies Vanden Bempt
- Disciplines:Systems biology
Affiliations
- Laboratory of Experimental Hematology (Division)
Member
From1 Feb 2020 → 8 Nov 2021 - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven Center for Cancer Biology) (Division)
Member
From15 Sep 2013 → Today
Projects
1 - 3 of 3
- Cooperation between N-MYC overexpression and epiginetic deregulation in peripheral T cell lymphomaFrom1 Oct 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Extensive preclinical validation of combinations of targeted treatment for peripheral T cell lymphomaFrom10 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Study Of Cooperating Oncogenes In The Development Of T-Cell Acute Lymphoblastic Leukemia Using CRISPR/Cas-Generated Cell And Mouse Models.From15 Sep 2013 → 31 Dec 2018Funding: IWT personal funding - strategic basic research grants, BOF - Doctoral projects
Publications
1 - 10 of 12
- Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified(2021)
Authors: Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Gregor Verhoef, Lucienne Michaux, Thomas Tousseyn, Jan Cools, Daan Dierickx
Number of pages: 19 - A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer(2021)
Authors: Ayse Bassez, Hanne Vos, Laurien Van Dyck, Giuseppe Floris, Ingrid Arijs, Christine Desmedt, Marlies Vanden Bempt, Ines Nevelsteen, Kathleen Lambein, Kevin Punie, et al.
Pages: 820 - +Number of pages: 40 - A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling(2020)
Authors: Junbin Qian, Siel Olbrecht, Hanne Vos, Hakki Emre Etlioglu, Els Wauters, Pieter Busschaert, Ayse Bassez, Marlies Vanden Bempt, Birgit Weynand, Yannick Van Herck, et al.
Pages: 745 - 762Number of pages: 18 - Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia(2019)
Authors: Michaël Broux, Cristina PRIETO FERNANDEZ, Sofie Demeyer, Marlies Vanden Bempt, Llucia Alberti Servera, Inge Lodewijckx, Jan Cools
Pages: 1323 - 1336Number of pages: 14 - Oncogene mechanismen van fusiegenen in hematologische aandoeningen(2018)
Authors: Marlies Vanden Bempt, Jan Cools
- Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia(2018)
Authors: Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Ellen Geerdens, Charles De Bock, Jan Cools
Pages: 271 - +Number of pages: 22 - EML1–ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model(2018)
Authors: Kim De Keersmaecker, Marlies Vanden Bempt, Peter Vandenberghe, Jan Cools
Number of pages: 5 - HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development(2018)
Authors: Charles De Bock, Sofie Demeyer, Sandrine Degryse, Delphine Verbeke, Marlies Vanden Bempt, Ellen Geerdens, Simon Bornschein, Rik Gijsbers, Jan Cools
Pages: 616 - 631 - Mutant JAK3 signaling is increased by loss of wild type JAK3 or by acquiring secondary JAK3 mutations in T-ALL(2018)
Authors: Sandrine Degryse, Simon Bornschein, Charles De Bock, Marlies Vanden Bempt, Sofie Demeyer, Ellen Geerdens, Jan Cools
Pages: 421 - 425 - ALK-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene(2017)
Authors: Marlies Vanden Bempt, Julio Antonio Finalet Ferreiro, Ellen Geerdens, Anne Uyttebroeck, Lucienne Michaux, Timothy Devos, Peter Vandenberghe, Thomas Tousseyn, Jan Cools, Iwona Krajewska
Pages: 1605 - 1616