Researcher
Marinee Chuah
- Keywords:Medicine
- Disciplines:Other basic sciences not elsewhere classified
Affiliations
- Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Division of Gene Therapy & Regenerative Medicine (Research group)
Member
From19 Apr 2011 → Today - Cell Biology and Histology (Department)
Member
From1 Oct 2010 → 31 Dec 2013 - Cell Biology and Histology (Department)
Member
From1 Oct 2010 → 30 Apr 2012
Projects
1 - 10 of 11
- SRP-Groeifinanciering: “RESTORE”: DEVELOPMENT OF INNOVATIVE GENE THERAPIES FOR GENETIC MUSCLE DISORDERSFrom1 Oct 2022 → TodayFunding: BOF - projects
- CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular DiseaseFrom1 Jan 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease (OZR EU Bonus).From1 Jan 2019 → 31 Dec 2023Funding: BOF - Other initiatives
- "CURE-DMD": Development of Next-Generation Gene Therapy for Duchenne Muscular DystrophyFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Financing IOF-program GEAR: Hyperactieve Expressie-modulesFrom1 Apr 2014 → 31 Mar 2020Funding: IOF - Industrial Research Fund
- SRP (Groeiers): Next-generation gene therapy by computational vector design and immune stealth nanotechnologyFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - Concerted Research Project from 1994
- In vivo genome engineering based on the CRISPR / Cas system: a new platform for functional genome analysis and gene therapyFrom1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Development of novel "immune stealth" nanotechnology for gene therapy of hemophilia: pre-clinical validation and underlying mechanismsFrom1 Oct 2013 → 30 Jun 2014Funding: FWO fellowships
- Cardiovascular and muscle-specific "targeting" for gene therapy of neuromuscular disordersFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Immune stealth nanotechnology for gene therapy of hemophilia 'A': mechanisms and translational implicationsFrom1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 64
- Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons(2020)
Authors: Jaitip Tipanee, Mario Di Matteo, Warut Tulalamba, Ermira Samara-Kuko, Jiri Keirsse, Jo A Van Ginderachter, Marinee K Chuah, Thierry VandenDriessche
Pages: 1309-1329 - Next-generation muscle-directed gene therapy by in silico vector design(2019)
Authors: Shilpita Sarcar, Warut Tulalamba, Melvin Rincon Acelas, Jaitip Tipanee, Hong Quang Pham, Hanneke Evens, Dimitri Boon, E. Samara-Kuko, Marleen Keyaerts, Mariana Loperfido, et al.
Pages: 492 - Genome Editing for Myotonic Dystrophy Type 1.(2019)
Authors: Sumitava Dastidar, Marinee K Chuah
- Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells(2018)
Authors: Sumitava Dastidar, Simon Ardui, Kshitiz Singh, Debanjana Majumdar, Nisha Nair, Yanfang Fu, Deepak Reyon, Ermira Samara, Mattia FM Gerbil, Arnaud F. Klein, et al.
Pages: 8275-8298 - A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity(2018)
Authors: Kyle Chamberlain, Jalish Mahmud Riyad, Tyrone Garnett, Erik Kohlbrenner, Ananda Mookerjee, Firas Elmastour, Ludovic Benard, Jiqiu Chen, Thierry VandenDriessche, Marinee K Chuah, et al.
Pages: 927-937 - Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9(2018)
Authors: Kshitiz Singh, Hanneke Evens, Nisha Nair, Melvin Rincon Acelas, Shilpita Sarcar, Ermira Samara, Marinee K Chuah, Thierry VandenDriessche
Pages: 1241-1254 - Haemophilia gene therapy(2018)
Authors: Hanneke Evens, Marinee K Chuah, Thierry VandenDriessche
Pages: 50-59 - Hyperactive Factor IX Padua(2018)
Authors: Thierry Vandendriessche, Marinee Chuah
Pages: 14-16 - Preclinical and clinical advances in transposon-based gene therapy(2017)
Authors: Jaitip Tipanee, Yoke Chin Chai, Thierry VandenDriessche, Marinee K Chuah
- Transposons(2017)
Authors: Jaitip Tipanee, Thierry VandenDriessche, Marinee K Chuah
Pages: 1087-1104
Patents
1 - 10 of 10
- Vectors for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Muscle-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Optimized liver-specific expression systems for fviii and fix (Inventor)
- Novel combination of nucleic acid regulatory elements and methods and uses thereof (Inventor)
- Novel combination of nucleic acid regulatory elements and methods and uses thereof (Inventor)
- Muscle-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Vector for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Vectors for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Endothelium-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Cardiomyocyte-derived nucleic acid regulatory elements and methods and use thereof (Inventor)