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Researcher
Mieke Dewerchin
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cardiac and vascular medicine
- See also: Mieke Dewerchin (Flanders Institute for Biotechnology)
Affiliations
- Carmeliet Lab (Research group)
Member
From1 Jan 2017 → Today - Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 1999 → 30 Sep 2005
Projects
11 - 16 of 16
- Matricellular proteins, Thrombospondin-2 en SPARC (Osteonectine) protect against heart failure.From1 Oct 2009 → 30 Sep 2012Funding: FWO fellowships
- Matricellular proteins: crucial regulators of cardiac remodelingFrom1 Oct 2009 → 31 Mar 2010Funding: Own budget, for example: patrimony, inscription fees, gifts
- Laser capture microdissection (LCM) and analysis.From20 Oct 2008 → 19 Apr 2015Funding: Hercules - Small and Medium size research infrastructure
- Analysis via a 6-color BD FACSCanto TM II cytometer.From20 Oct 2008 → 19 Apr 2015Funding: Hercules - Small and Medium size research infrastructure
- Matricellular proteins, thrombospondin-2 and SPARC (osteonectin), protect against heart failure.From1 Oct 2008 → 30 Sep 2009Funding: BOF - Other initiatives
- Role of PIGF and therapeutic potential of PIGF-inhibition in inflammatory disease.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 118
- COVID-19 plasma induces subcellular remodelling within the pulmonary microvascular endothelium.(2024)
Authors: Mieke Dewerchin
Pages: 107277 - How Does Temporal and Sequential Delivery of Multiple Growth Factors Affect Vascularization Inside 3D Hydrogels?(2024)
Authors: Mieke Dewerchin
- Detailed protocol for a corneal thermal cauterization-based (lymph-)angiogenesis assay in mice(2023)
Authors: Anh-Co Truong, Koen Veys, Mieke Dewerchin, Peter Carmeliet
- Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells(2023)
Authors: Flore Sneyers, Martijn Kerkhofs, Rita La Rovere, Mieke Dewerchin, Geert Bultynck
- VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway(2023)
Authors: Mieke Dewerchin, Peter Carmeliet
- Covid-19 Plasma Exposure Causes Transcriptional, Morphological, And Functional Changes Within The Pulmonary Microvascular Endothelium(2023)
Authors: Mieke Dewerchin
- Prioritization and functional validation of target genes from single-cell transcriptomics studies(2023)
Authors: Anh-Co Truong, Mieke Dewerchin, Peter Carmeliet
- The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution(2023)
Authors: Bram Boeckx, Sander Jansen, Simon Feys, Stijn Verleden, Laurens Liesenborghs, Sébastien Dumas, Mila Borri, Liliana Sokol, Anh-Co Truong, Jan Gunst, et al.
Pages: 520 - 535 - A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds(2023)
Authors: Mieke Dewerchin, Peter Carmeliet
Pages: 680 - 692 - Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells(2022)
Authors: Mieke Dewerchin, Peter Carmeliet