Researcher
Mieke Dewerchin
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cardiac and vascular medicine
- See also: Mieke Dewerchin (Flanders Institute for Biotechnology)
Affiliations
- Carmeliet Lab (Research group)
Member
From1 Jan 2017 → Today - Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 1999 → 30 Sep 2005
Projects
1 - 10 of 16
- Endothelial immunosuppressive mystery genes in spleen for alternative immunotherapy: dissecting their features via lipid nanoparticle-based target validationFrom10 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mass cytometry by time-of-flight: next-generation flow cytometry for multiplexed single cell analysisFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Meningeal cells contribute to cortical neurogenesis in postnatal brainFrom13 Apr 2015 → 15 Mar 2016Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of the pyruvate kinase isoforms PKM1 and PKM2 in endothelial cell metabolism and angiogenesisFrom1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- The serine synthesis pathway: an unexplored metabolic pathway in endothelial cells, regulating angiogenesis?From1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships
- Understanding the metabolism of lymphatic endothelial cells.From1 Oct 2014 → 27 Feb 2017Funding: FWO fellowships
- The role of PFKFB3 in tumor angiogenesis and vessel normalizationFrom1 Sep 2014 → 18 Apr 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Endothelial glutamine metabolism : target for anti-tumor angiogenesis therapy.From1 Jan 2013 → 31 Dec 2017Funding: Private funding of national origin - undefined
- Glycosylatie van angiogene factoren via de hexosamine biosyntheseweg, een nutriënten-sensor met een functie in metabole signalering in angiogenese?From1 Sep 2012 → 18 Oct 2016Funding: FWO fellowships
- Investigating the role of endothelial glutamine metabolism in the control of angiogenesis.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 118
- Role of glutamine and interlinked asparagine metabolism in vessel formation(2017)
Authors: Hongling Huang, Saar Vandekeere, Joanna Kalucka, Laura Bierhansl, Annalisa Zecchin, Jermaine Goveia, Bart Ghesquière, Mieke Dewerchin, Guy Eelen, Peter Carmeliet
Pages: 2334 - 2352 - Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy(2016)
Authors: Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Kalucka, Andreas Pircher, Bernard Thienpont, Laure-Anne Teuwen, Sandra Schoors, Bram Boeckx, et al.
Pages: 968 - 985 - De novo design of a biologically active amyloid(2016)
Authors: Rodrigo Gallardo, Frederik De Smet, Filip Claes, Laleh Khodaparast, Ladan Khodaparast, Tobias Langenberg, Maxime Siemons, Manoj Kumar Gautam, Manu Beerens, Aernout Luttun, et al.
- Notch: a molecular hub controlling the metabolic adaptations responsible for redox homeostasis during endothelial quiescence(2016)
Authors: Rindert Missiaen, Mieke Dewerchin, Peter Carmeliet
- Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities(2016)
Authors: Jermaine Goveia, Andreas Pircher, Lena-Christin Conradi, Joanna Kalucka, Mieke Dewerchin, Guy Eelen, Peter Carmeliet
Pages: 1134 - 1142 - Vascular endothelial growth factor: a neurovascular target in neurological diseases(2016)
Authors: Christian Lange, Mieke Dewerchin, Peter Carmeliet
Pages: 439 - 454 - A key role for transketolase-like 1 in tumor metabolic reprogramming(2016)
Authors: Mieke Dewerchin, Bart Ghesquière, Guy Eelen, Peter Carmeliet
Pages: 51875 - 51897 - Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis(2016)
Authors: Christian Lange, Guy Eelen, Annelies Quaegebeur, Ruben Boon, Hui Zhao, Bram Boeckx, Diether Lambrechts, Mieke Dewerchin, Peter Carmeliet
Pages: 924 - 41 - Meningeal cells contribute to cortical neurogenesis in postnatal brain(2016)
Authors: Peter Carmeliet, Mieke Dewerchin
- The oxygen sensor PHD2 controls dendritic spines and synapses via modification of filamin A(2016)
Authors: Christian Lange, Guy Eelen, Matthew Holt, Dirk Daelemans, Bart Ghesquière, Mieke Dewerchin, Peter Carmeliet
Pages: 2653 - 67