Researcher
Maria Debiec-Rychter
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Laboratory for Genetics of Malignant Disorders (Division)
Member
From1 Jul 2009 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → 30 Jun 2009
Projects
1 - 4 of 4
- Human soft tissue sarcomas xenograft mouse models as an opportunity to improve the therapeutic options for patients.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Identification of novel protein kinase targets for the improvement of gastrointestinal stromal tumor (GIST) therapy: a paradigm for the optimisation of kinase targeted therapies.From1 Jan 2011 → 31 Dec 2016Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- The biological and therapeutic importance of CCK-2/gastrin receptor in gastrointestinal stromal tumors (GISTs).From1 Jan 2009 → 31 Dec 2012Funding: FWO research project
Publications
11 - 20 of 193
- Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors(2020)
Authors: Yannick Wang, Agnieszka Wozniak, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski
- The prognostic role of BRAF and WNT pathways activation in kinase inhibitors-naive clinical stage III cutaneous melanoma(2020)
Authors: Maria Debiec-Rychter
Pages: 348 - 357 - Anti-tumor activity of the MDM2-TP53 inhibitor BI-907828 in dedifferentiated liposarcoma patient-derived xenograft models harboring MDM2 amplification(2020)
Authors: Agnieszka Wozniak, Daphne Hompes, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski
Pages: 546 - 554 - Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells(2020)
Authors: Maria Debiec-Rychter, Patrick Schöffski, Agnieszka Wozniak
- Cardiac intimal sarcoma: A case report of a rare tumor with peculiar histopathological findings(2019)
Authors: Raf Sciot, Maria Debiec-Rychter, Louis Libbrecht
Pages: 440 - 443 - Detection of Circulating Tumor DNA in Patients With Uterine Leiomyomas(2019)
Authors: Lien Spans, Maria Debiec-Rychter
- Assessment of the platelet-derived growth factor receptor alpha antibody olaratumab in a panel of patient-derived soft tissue sarcoma xenografts(2019)
Authors: Agnieszka Wozniak, Britt Van Renterghem, Maria Debiec-Rychter, Raf Sciot, Daphne Hompes, Patrick Schöffski
- Molecular Comparison of Imatinib-Naive and Resistant Gastrointestinal Stromal Tumors: Differentially Expressed microRNAs and mRNAs(2019)
Authors: Raf Sciot, Patrick Schöffski, Maria Debiec-Rychter
- Establishment and Characterization of Histologically and Molecularly Stable Soft-tissue Sarcoma Xenograft Models for Biological Studies and Preclinical Drug Testing(2019)
Authors: Agnieszka Wozniak, Bram Boeckx, Daphne Hompes, Marguerite Stas, Hazem Wafa, Diether Lambrechts, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski
Pages: 1168 - 1178 - Clear Cell Odontogenic Carcinoma: Occurrence of EWSR1-CREB1 as Alternative Fusion Gene to EWSR1-ATF1(2019)
Authors: Maria Debiec-Rychter
Pages: 225 - 230