Researcher
Marc Hoylaerts
- Disciplines:Molecular and cell biology, Cardiac and vascular medicine
Affiliations
- Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 1999 → 30 Sep 2019
Projects
1 - 10 of 21
- PEAR1 (epi)genetic profiling in population studies to unravel its potential role in platelet and endothelial cell function variabilityFrom1 Jan 2015 → 31 Mar 2017Funding: FWO research grant KAN
- (Epi)-genetic PEAR1 PHenotyping in HEmatopoietic Specification (EPHES).From1 Oct 2014 → 31 Mar 2017Funding: FWO fellowships
- Platelet Endothelial Aggregation Receptor 1 in endothelial cell biology.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Bacterial pathogens modulate thrombin activity to overcome innate defence mechanisms.From1 Oct 2013 → 22 May 2019Funding: FWO fellowships
- Regulatory mechanisms of PEAR1 expression in myeloid cell-lineage specification.From1 Oct 2013 → 30 Sep 2014Funding: BOF - Other initiatives
- Fibrinolysis and proteolysis in bacterial spread and tissue destruction.From1 Oct 2012 → 20 Dec 2016Funding: FWO fellowships
- PEAR1 in the regulation of platelet function and in thrombopoiesis.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- The role of PEAR1 (Platelet Endothelial Aggregation Receptor1) for endothelial cell.From1 Oct 2011 → 18 Nov 2015Funding: FWO fellowships
- Role of PAI-1 and TAFI in the aetiology of IBD and as prognostic marker or/and therapeutic target to prevent venous thromboembolism in IBD patients.From1 Oct 2011 → 30 Sep 2015Funding: FWO fellowships
- Cellular Interactions and Heterogeneity in Ischemic Cardiovascular DiseaseFrom1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
Publications
31 - 40 of 176
- Clumping factor A, von Willebrand factor-binding protein and von Willebrand factor anchor Staphylococcus aureus to the vessel wall(2017)
Authors: Laurens Liesenborghs, Marijke Peetermans, Marc Hoylaerts, Ruth Heying, Peter Verhamme, Thomas Vanassche
Pages: 1009 - 1019 - PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population(2017)
Authors: Wenyi Yang, Thibault Petit, Nicholas Cauwenberghs, Zhenyu Zhang, Lutgarde Thijs, Benedetta Izzi, Christophe Vandenbriele, Fangfei Wei, Lotte Jacobs, Marc Hoylaerts, et al.
Pages: 45 - A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling(2017)
Authors: Marc Hoylaerts
Pages: 883 - 895 - The impact of flow on Staphylococcus aureus - endothelium interactions in infective endocarditis(2017)
Authors: Jorien Claes, Ruth Heying, Peter Verhamme, Marc Hoylaerts
- ADAMTS13 deficiency promotes microthrombosis in a murine model of diet-induced liver steatosis(2017)
Authors: Lotte Geys, Dries Bauters, Elien Roose, Claudia Tersteeg, Karen Vanhoorelbeke, Marc Hoylaerts, Roger Lijnen, Ilse Scroyen
Pages: 19 - 26 - Heme oxygenase-1 and chronic kidney disease: A translational study of oxidative stress and atherogenesis(2016)
Authors: Bert Bammens, Marc Hoylaerts
Number of pages: 195 - Allele-specific DNA methylation capacitates PEAR1 enhancer activity(2016)
Authors: Benedetta Izzi, Elena Pistoni, Diether Lambrechts, Catherine Verfaillie, Peter Verhamme, Kathleen Freson, Marc Hoylaerts
Pages: 1003 - 1012 - Dextran sulfate triggers platelet aggregation via direct activation of PEAR1(2016)
Authors: Christophe Vandenbriele, Yiting Sun, Maarten Criel, Benedetta Izzi, Thomas Vanassche, Peter Verhamme, Marc Hoylaerts
Pages: 365 - 372 - Shear-resistant Binding to Von Willebrand Factor Allows Staphylococcus Lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis(2016)
Authors: Laurens Liesenborghs, Marijke Peetermans, Christophe Vandenbriele, Maarten Criel, Willy Peetermans, Thomas Vanassche, Marc Hoylaerts, Peter Verhamme
Pages: 1148 - 56 - Absence of Pear1 does not affect murine platelet function in vivo(2016)
Authors: Maarten Criel, Benedetta Izzi, Christophe Vandenbriele, Laurens Liesenborghs, Elizabeth Jones, Thomas Vanassche, Peter Verhamme, Marc Hoylaerts
Pages: 76 - 83