Researcher
Marc Bracke
- Disciplines:Cancer prevention, Cell signalling, Cellular interactions and extracellular matrix, Cancer epidemiology, Cancer diagnosis, Cytoskeleton, Cancer biology, Cell death, Cell division, Cell growth and development, Cell movement, Cancer therapy, Transcription and translation, Oncology not elsewhere classified, Intracellular compartments and transport, Molecular and cell biology not elsewhere classified, Membrane structure and transport, Posttranslational modifications, Stem cell biology, Structural biology
Affiliations
- Department of Human Structure and Repair (Department)
Member
From1 Oct 2018 → 30 Sep 2022 - Department of Radiation oncology and experimental cancer research (Department)
Member
From1 Oct 2000 → 30 Sep 2018
Projects
1 - 10 of 34
- Exosomal miRNAs as a biomarker for early targeted therapy response in advanced triple negative breast cancerFrom1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Glucocorticoid and selective glucocorticoid receptor modulator effects on tumour eco-systemFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships, BOF - Other initiatives
- Development of small-molecule inhibitors of nonmuscle myosin II as chemical tools and antimetastatic therapeutics (CONFIDENTIAL)From1 Oct 2013 → 30 Sep 2017Funding: BOF - Doctoral projects
- The metastic niche: preparation, function and translational evidence of a permissieve micro environment for cancer disseminationFrom1 Jan 2013 → 31 Oct 2019
- Resistance to EGFR-targeted therapy in colorectal cancer: biological significance of stromal-derived neuregulin-1From1 Jan 2013 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- Exosomes: nanomaps for metastatic niche formationFrom1 Oct 2012 → 30 Sep 2019Funding: FWO fellowships, BOF - Other initiatives
- Cancer cell-derived exosomes and their role in the tumor ecosystemFrom1 Oct 2012 → 30 Sep 2013Funding: Nonprofit institution or equivalents
- The formation of metastases is the main cause of cancer-related mortalityFrom1 Oct 2012 → 30 Sep 2018Funding: FWO fellowships, BOF - Other initiatives
- Hit-to-lead Evaluation of Chalcone Analogs Useful for Anti-Invasive Cancer TherapyFrom1 Aug 2012 → 30 Apr 2014Funding: IOF - Industrial Research Fund
- IVIS Lumina II Bioluminescence camera for laboratory animal researchFrom15 Jun 2012 → 30 Jun 2016Funding: BOF - Other initiatives
Publications
1 - 10 of 181
- Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models(2019)
Authors: Yves Depetter, Rob De Vreese, Sophie Goethals, Elien Vandoorn, Alien Laevens, Jonas Steenbrugge, Pascal de Tullio, Marc Bracke, Matthias D'hooghe
Pages: 735 - 747 - Nieuwe inzichten betreffende metastasen(2018)
Authors: Marc Bracke
Pages: 1261 - 1264 - Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research(2018)
Authors: Edward Geeurickx, Elisa Heyrman, Jan Van Deun, Joeri Tulkens, Glenn Vergauwen, Ilkka Miinalainen, Pieter-Jan Van Bockstal, Thomas De Beer, Marca Wauben, Ester Nolte-'t Hoen, et al.
Number of pages: 1 - Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo(2018)
Authors: Emiel De Jaeghere, Elly De Vlieghere, Jasper Van Hoorick, Sandra Van Vlierberghe, Glenn Wagemans, Marleen Praet, Matthieu Boone, Rouba Ghobeira, Nathalie De Geyter, Marc Bracke, et al.
Pages: 95 - 105 - Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts(2018)
Authors: Zuzanna Drebert, Elly De Vlieghere, Jolien Bridelance, Marc Bracke, Ilse Beck
Pages: 332 - 342 - Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor(2017)
Authors: Zuzanna Drebert, Mark MacAskill, Dahlia Doughty-Shenton, Marc Bracke, Patrick WF Hadoke, Ilse Beck
Pages: 19 - 30 - A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer(2017)Volume: 32
Authors: Mieke Van Bockstal, Glenn Vergauwen, Kathleen Lambein, Veronique Cocquyt, Louis Libbrecht, Hannelore Denys, Marc Bracke
Pages: S48 - S48 - Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth(2017)
Authors: Lore Lapeire, An Hendrix, Evelyne Lecoutere, Mieke Van Bockstal, Dawn Maynard, Rudy Van den Broecke, Cathérine Müller, Marc Bracke, Veronique Cocquyt, Hannelore Denys
Pages: 47239 - 47249 - Discovery of (S)-3U+2032-hydroxyblebbistatin and (S)-3U+2032-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties(2017)
Authors: Sigrid Verhasselt, Kristof Van Hecke, Rik Van Deun, Marc Bracke, Christian Stevens
Pages: 2104 - 2118 - Pharmacological evaluation of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone(2016)
Authors: Tine De Ryck, Marc Bracke, Christian Stevens
Number of pages: 1
Patents
1 - 1 of 1
- HDAC6 Inhibitors and uses thereof (Inventor)