Researcher
Malgorzata Domagalska
Affiliations
- Molecular Parasitology (Research unit)
Member
From1 Mar 2015 → Today - Molecular Parasitology (Research unit)
Member
From28 Feb 2015 → 16 Apr 2015
Projects
1 - 6 of 6
- Cellular, molecular and functional characterization of quiescence in Leishmania donovani, the etiological agent of visceral leishmaniasisFrom27 Apr 2022 → Today
- Investigating the role of chromatin accessibility in the global transcription regulation in Leishmania quiescent cellusing multiomic single cell approachesFrom1 Dec 2021 → 31 Jan 2023
- Mechanisms of P. vivax chloroquine resistance: a transcriptomic/transgenic approachFrom1 Jan 2021 → Today
- Single cell transcriptomics of Leishmania donovani throughout its development in its natural sand fly vector Phlebotomus argentipesFrom20 Oct 2020 → 31 Jan 2023
- Aneuploidy and mosaicism: a strategy for early adaptation to drug pressure in LeishmaniaFrom17 Apr 2020 → Today
- Aneuploidy and mosaicism: a strategy for early adaptation todrug pressure in LeishmaniaFrom1 Oct 2018 → Today
Publications
1 - 10 of 27
- High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani(2022)
Authors: Gabriel Heringer Negreira, Pieter Monsieurs, H Imamura, I Maes, Nada Kuk, Akila Yagoubat, Frederik Van den Broeck, Yvon Sterkers, JC Dujardin, Malgorzata Domagalska
Pages: 293-305 - Transcriptional shift and metabolic adaptations during Leishmania quiescence using stationary phase and drug pressure as models(2022)
Authors: Marlene Jara Portocarrero, Michael P Barrett, I Maes, Clement Regnault, H Imamura, Malgorzata Domagalska, Jean-Claude Dujardin
- Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania(2022)
Authors: Bart Cuypers, Pieter Meysman, Ionas Erb, Wout Bittremieux, Dirk Valkenborg, Geert Baggerman, Inge Mertens, Shyam Sundar, Basudha Khanal, Cedric Notredame, et al.
Pages: e1010848 - Genomic and phenotypic characterization of experimentally selected resistant Leishmania donovani reveals a role for dynamin-1-like protein in the mechanism of resistance to a novel antileishmanial compound(2022)
Authors: Aya Emad HEFNAWY, Gabriel Heringer Negreira, Marlene Jara Portocarrero, James A Cotton, I Maes, Erika D`Haenens, H Imamura, Bart Cuypers, Pieter Monsieurs, Christina Mouchtoglou, et al.
- Amino-substituted 3-aryl- and 3-heteroarylquinolines as potential antileishmanial agents(2021)
Authors: Jared T Hammill, Vitaliy M Sviripa, Liliia M Kril, Diana Ortiz, Corinne M Fargo, Ho Shin Kim, Yizhe Chen, Jonah Rector, Amy L Rice, Malgorzata Domagalska, et al.
Pages: 12152-12162 - Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level(2020)
Authors: H Imamura, Pieter Monsieurs, Marlene Jara Portocarrero, Mandy Sanders, I Maes, M Vanaerschot, Matthew Berriman, James A Cotton, Jean-Claude Dujardin, Malgorzata Domagalska
- The absence of C-5 DNA methylation in Leishmania donovani allows DNA enrichment from complex samples(2020)
Authors: Bart Cuypers, Franck Dumetz, Pieter Meysman, Kris Laukens, G. De Muylder, Jean-Claude Dujardin, Malgorzata Domagalska
- Next-generation molecular surveillance of TriTryp diseases(2020)
Authors: Malgorzata Domagalska, Jean-Claude Dujardin
Pages: 356-367 - Non-Leishmania parasite in fatal visceral leishmaniasis-like disease, Brazil(2020)
Authors: Malgorzata Domagalska, Jean-Claude Dujardin
Pages: 388 - Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent(2019)
Authors: Malgorzata Domagalska, H Imamura, Mandy Sanders, Frederik Van den Broeck, Narayan Raj Bhattarai, M Vanaerschot, I Maes, Erika D`Haenens, Keshav Rai, Suman Rijal, et al.