Researcher
Lutz Nuhn
- Disciplines:Clinical trials, Pharmacognosy and phytochemistry, Pharmaceutics, Other pharmaceutical sciences, Toxicology and toxinology, Pharmacology, Clinical pharmacy, Particle design and technology, Vaccines, Biomarker discovery
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Jan 2015 → 30 Sep 2018
Projects
1 - 2 of 2
- Monitoring ketal-hydrolysis in synthetic polymer nanoparticles by FRET in living systemsFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Induction of safe but potent anti-tumour responses via lymph node focused nanoparticle-mediated immune activationFrom1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
Publications
1 - 10 of 28
- Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent(2020)
Authors: Jana De Vrieze, Simon Van Herck, Lutz Nuhn, Bruno De Geest
- A synthetic, transiently thermoresponsive homopolymer with UCST behaviour within a physiologically relevant window(2019)
Authors: Zhiyue Zhang, Hui Li, Sabah Kasmi, Simon Van Herck, Kim Deswarte, Richard Hoogenboom, Lutz Nuhn, Bruno De Geest
Pages: 7866 - 7872 - Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses(2018)
Authors: Lutz Nuhn, Stefaan De Koker, Francis Combes, Kim Deswarte, Yupeng Li, Stefan Lienenklaus, Niek Sanders, Sunil A David, Jan Tavernier, Bruno De Geest
- Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through strain promoted azide alkyne cycloaddition ligation(2018)
Authors: Lutz Nuhn, Evangelia Bolli, Sam Massa, Isabel Vandenberghe, Kiavash Movahedi, Bart Devreese, Jo A Van Ginderachter, Bruno De Geest
Pages: 2394 - 2405 - FRET monitoring of intracellular ketal hydrolysis in synthetic nanoparticles(2018)
Authors: Lutz Nuhn, Simon Van Herck, Andreas Best, Kim Deswarte, Maria Kokkinopoulou, Ingo Lieberwirth, Kaloian Koynov, Bruno De Geest
Pages: 10760 - 10764 - Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates(2018)
Authors: Simon Van Herck, Kim Deswarte, Lutz Nuhn, Yupeng Li, Niek Sanders, Stefan Lienenklaus, Stefaan De Koker, Sunil A David, Bruno De Geest
Pages: 14300 - 14307 - Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist(2018)
Authors: Lutz Nuhn, Lien Van Hoecke, Kim Deswarte, Yupeng Li, Stefaan De Koker, Sunil A David, Bruno De Geest
Pages: 643 - 651 - pH-Sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated ester scaffolds : synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish(2018)
Authors: Alexandra Van Driessche, Agnese Kocere, Hannelien Everaert, Lutz Nuhn, Simon Van Herck, Gareth Griffiths, Federico Fenaroli, Bruno De Geest
Pages: 8587 - 8596 - SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles(2017)
Authors: Nadine Leber, Leonard Kaps, Misbah Aslam, Jonathan Schupp, Alexander Brose, David Schäffel, Karl Fischer, Mustafa Diken, Dennis Strand, Kaloian Koynov, et al.
Pages: 10 - 23 - Cancer cell lysate entrapment in CaCO3 engineered with polymeric TLR-agonists : immune-modulating microparticles in view of personalized antitumor vaccination(2017)
Authors: Lien Lybaert, Keun Ah Ryu, Lutz Nuhn, Alfred C Chon, Aaron P Esser-Kahn, Bruno De Geest
Pages: 4209 - 4217