Researcher
Ludo Van Den Bosch
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Responsible
From1 Oct 2018 → Today - Van Den Bosch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2012 → Today - Research Group Experimental Neurology (Division)
Member
From1 Oct 2002 → 31 Dec 2011
Projects
1 - 10 of 60
- Investigating the pathological mechanisms underlying KIF5A mutations in ALSFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Engineering Functional 3D Neuromuscular Junctions: Investigating Myogenic Stem Cell Differentiation and Integration with iPSC-Derived Motor NeuronsFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating fatty acid toxicity in amyotrophic lateral sclerosisFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Investigating the therapeutic potential of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS) using human induced pluripotent stem cells (iPSCs).From1 May 2023 → TodayFunding: Other federal public and semi-governmental institutions
- FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanismsFrom19 Apr 2023 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Creating iPSC-derived 3D human neuromuscular junctions to investigate amyotrophic lateral sclerosis (ALS)From15 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating mechanisms of RNA misprocessing in Amyotrophic Lateral SclerosisFrom8 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Determination and investigation of the therapeutic targets of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS)From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Creation of a humanized mouse model for demyelinating peripheral neuropathies as a platform for therapeutic testing.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating the role of DNA damage and repair in the selective motor neuron death during amyotrophic lateral sclerosis (ALS)From15 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
41 - 50 of 231
- The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis(2021)
Authors: Joni Vanneste, Ludo Van Den Bosch
- Reviewing the availability, efficacy and clinical utility of Telepsychology in dialectical behavior therapy (Tele-DBT)(2021)
Authors: Roland Sinnaeve, Tom Van Daele, Ludo Van Den Bosch
- In silico prediction of in vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention(2021)
Authors: Daniele Raimondi, Gabriele Orlando, Emiel Michiels, Ludo Van Den Bosch, Yves Moreau, Frederic Rousseau, Joost Schymkowitz
Pages: 3473 - 3479 - Histone Deacetylase Inhibition Regulates Lipid Homeostasis in a Mouse Model of Amyotrophic Lateral Sclerosis(2021)
Authors: Thibaut Burg, Elisabeth Rossaert, Philip Van Damme, Ludo Van Den Bosch
- Axonal transport defects in C9orf72 ALS/FTD: the role of dipeptide repeat proteins(2021)
Authors: Laura Fumagalli, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie
- Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition(2021)
Authors: Katarina Dittlau, Laura Fumagalli, Elisabeth Rossaert, Jimmy Beckers, Maurilio Sampaolesi, Philip Van Damme, Ludo Van Den Bosch
Pages: 2213 - 2227 - Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices(2021)
Authors: Katarina Dittlau, Elisabeth Rossaert, Jimmy Beckers, Maurilio Sampaolesi, Philip Van Damme, Ludo Van Den Bosch
- Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS(2021)
Authors: Ludo Van Den Bosch
- Reply to 'TDP43 aggregates: the 'Schrodinger's cat' in amyotrophic lateral sclerosis'(2021)
Authors: Ludo Van Den Bosch
Pages: 515 - 515 - Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction(2021)
Authors: Ludo Van Den Bosch
Pages: 2471 - 2485
Patents
1 - 4 of 4