Researcher
Ludo Van Den Bosch
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Responsible
From1 Oct 2018 → Today - Van Den Bosch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2012 → Today - Research Group Experimental Neurology (Division)
Member
From1 Oct 2002 → 31 Dec 2011
Projects
1 - 10 of 60
- Investigating the pathological mechanisms underlying KIF5A mutations in ALSFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Engineering Functional 3D Neuromuscular Junctions: Investigating Myogenic Stem Cell Differentiation and Integration with iPSC-Derived Motor NeuronsFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating fatty acid toxicity in amyotrophic lateral sclerosisFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Investigating the therapeutic potential of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS) using human induced pluripotent stem cells (iPSCs).From1 May 2023 → TodayFunding: Other federal public and semi-governmental institutions
- FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanismsFrom19 Apr 2023 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Creating iPSC-derived 3D human neuromuscular junctions to investigate amyotrophic lateral sclerosis (ALS)From15 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating mechanisms of RNA misprocessing in Amyotrophic Lateral SclerosisFrom8 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Determination and investigation of the therapeutic targets of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS)From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Creation of a humanized mouse model for demyelinating peripheral neuropathies as a platform for therapeutic testing.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating the role of DNA damage and repair in the selective motor neuron death during amyotrophic lateral sclerosis (ALS)From15 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
31 - 40 of 231
- CHEMICAL TOOLS TO INVESTIGATE THE MOLECULAR MECHANISMS OF HDAC6 IN HEALTH AND DISEASE(2022)
Authors: Carlotta Borgarelli, Robert Ciarán Prior, Wim De Borggraeve, Steven Verhelst, Ludo Van Den Bosch
Pages: S66 - S66 - PMP22 OVEREXPRESSION CAUSES LIPID RECYCLING DEFECTS THAT ALTERS THE PLASMA MEMBRANE IN CMT1A(2022)
Authors: Robert Ciarán Prior, Vincent de Laat, Jonas Dehairs, Philip Van Damme, Johan Swinnen, Ludo Van Den Bosch
Pages: S108 - S108 - IPSC-DERIVED MOTOR NEURONS REVEAL PROGRESSIVE MITOCHONDRIAL DYSFUNCTION IN AXONAL CMT SUBTYPES(2022)
Authors: Ludo Van Den Bosch
Pages: S137 - S137 - HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model(2022)
Authors: Robert Ciarán Prior, Elisabeth Rossaert, Alessio Silva, Philip Van Damme, Ludo Van Den Bosch
Pages: 3414 - 3430 - Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation(2022)
Authors: Lidia Yshii, Emanuela Pasciuto, Pierre Lemaitre, Marika Marino, James Dooley, Hannelore Kemps, Jérôme Wahis, Willy Gsell, Sebastian Munck, Robin Lemmens, et al.
Pages: 878 - + - Cellular Stress Induces Nucleocytoplasmic Transport Deficits Independent of Stress Granules(2022)
Authors: Thomas Vercruysse, Philip Van Damme, Dirk Daelemans, Ludo Van Den Bosch
- ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function(2022)
Authors: Valérie Bercier, Ludo Van Den Bosch
- Investigating the role of mutant TDP-43-ALS using human iPSC-derived motor neurons(2022)
Authors: Raheem Fazal, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie
- Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology(2022)
Authors: Evelien Van Schoor, Mathieu Vandenbulcke, Valérie Bercier, Rik Vandenberghe, Philip Van Damme, Ludo Van Den Bosch, Dietmar Thal
- Transcription factor-based differentiation of pluripotent stem cells to investigate the role of glial cells in FUS-linked ALS(2021)
Authors: Katrien Neyrinck, Catherine Verfaillie, Ludo Van Den Bosch
Patents
1 - 4 of 4