Researcher
Ludo Van Den Bosch
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Responsible
From1 Oct 2018 → Today - Van Den Bosch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2012 → Today - Research Group Experimental Neurology (Division)
Member
From1 Oct 2002 → 31 Dec 2011
Projects
1 - 10 of 60
- Investigating the pathological mechanisms underlying KIF5A mutations in ALSFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Engineering Functional 3D Neuromuscular Junctions: Investigating Myogenic Stem Cell Differentiation and Integration with iPSC-Derived Motor NeuronsFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating fatty acid toxicity in amyotrophic lateral sclerosisFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Investigating the therapeutic potential of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS) using human induced pluripotent stem cells (iPSCs).From1 May 2023 → TodayFunding: Other federal public and semi-governmental institutions
- FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanismsFrom19 Apr 2023 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Creating iPSC-derived 3D human neuromuscular junctions to investigate amyotrophic lateral sclerosis (ALS)From15 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating mechanisms of RNA misprocessing in Amyotrophic Lateral SclerosisFrom8 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Determination and investigation of the therapeutic targets of HDAC6 inhibition in amyotrophic lateral sclerosis (ALS)From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Creation of a humanized mouse model for demyelinating peripheral neuropathies as a platform for therapeutic testing.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating the role of DNA damage and repair in the selective motor neuron death during amyotrophic lateral sclerosis (ALS)From15 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
161 - 170 of 228
- Efficacy and cost-effectiveness of an experimental short-term inpatient Dialectical Behavior Therapy (DBT) program: study protocol for a randomized controlled trial(2014)
Authors: Ludo Van Den Bosch, Roland Sinnaeve
- Charcot-Marie-Tooth Disease and Other Peripheral Neuropathies(2014)
Authors: Veronick Benoy, Constantin van Outryve d'Ydewalle, Ludo Van Den Bosch
Pages: 269 - 325 - The role of histone deacetylase 6 (HDAC6) in neurodegeneration(2014)
Authors: Lawrence Van Helleputte, Veronick Benoy, Ludo Van Den Bosch
Pages: 1 - 13 - Prevention of intestinal obstruction reveals progressive neurodegeneration in mutant TDP-43 (A315T) mice(2014)
Authors: Sarah Herdewyn, Carla Cirillo, Ludo Van Den Bosch, Wim Robberecht, Pieter Vanden Berghe, Philip Van Damme
Pages: 24 - Charcot-Marie-Tooth Disease and Other Peripheral Neuropathies(2014)
Authors: Veronick Benoy, Ludo Van Den Bosch
Pages: 269 - 325 - The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding(2013)
Authors: Louis De Muynck, Sarah Herdewyn, Sander Beel, Ludo Van Den Bosch, Wim Robberecht, Philip Van Damme
Pages: 2541 - 2547 - Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats(2013)
Authors: Sarah Herdewyn, Louis De Muynck, Ludo Van Den Bosch, Wim Robberecht, Philip Van Damme
Pages: 2302 - 3 - Rapamycin increases survival in ALS mice lacking mature lymphocytes(2013)
Authors: James Dooley, Philip Van Damme, Adrian Liston, Wim Robberecht, Ludo Van Den Bosch
- Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice(2013)
Authors: Kim Staats, Lawrence Van Helleputte, Robin Lemmens, Philip Van Damme, Adrian Liston, Wim Robberecht, Ludo Van Den Bosch
Pages: 11 - 17 - Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS(2013)
Authors: Ludo Van Den Bosch, Philip Van Damme, Wim Robberecht
Pages: 1783 - 1790
Patents
1 - 4 of 4