Researcher
Luc Leyns
- Research Expertise:
- Early mouse development: phenotypic analysis.
- Transgenic mouse
- Wnt protein expression
- Gene expression analysis
- Embryonic Stem cells (ES cells): culture and differentiation
- Keywords:Biology
- Disciplines:Animal developmental and reproductive biology, Animal cell and molecular biology, Animal genetics, Developmental genetics, Cell growth and development, Cell signalling
- Users of research expertise:
- Early mouse development: phenotypic analysis.
- Transgenic mouse
- Wnt protein expression
- Gene expression analysis
- Embryonic Stem cells (ES cells): culture and differentiation
Affiliations
- Cell Genetics (Research group)
Responsible
From1 Oct 1998 → Today - Biology (Department)
Member
From1 Oct 2022 → Today - Biology (Department)
Member
From8 Apr 2019 → Today - Biology (Department)
Member
From1 Oct 1998 → Today
Projects
1 - 7 of 7
- Hadrosaur Bonebed Crime Scene Investigation: Evolution, ecology and extinction of the last megaherbivores of the latest CretaceousFrom1 Oct 2014 → 30 Sep 2020Funding: FWO fellowships
- Functional analysis of the conserved Iroquois homeobox genes in the formation and patterning of the mouse diencephalonFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships
- The role of microtubule stabilisation in neural induction/differentiation: Silica nanoparticles as a research toolFrom1 Oct 2011 → 30 Sep 2017Funding: FWO fellowships
- Differentiation of mouse embryonic stem cells towards skeletal muscle precursors through modulation of signalling pathway activity.From1 Jan 2011 → 12 Apr 2015Funding: IWT personal funding - strategic basic research grants
- Antero-posterior patterning by signalization factors in a mouse model of gastrulationFrom1 Jan 2009 → 31 Dec 2009Funding: FWO research grant KAN
- Multifoon confocale laser scanning microscoop voor imaging core faciliteit ter ondersteuning van onderzoek van de life sciences campus Jette en campus etterbeek -VUB.From1 Dec 2008 → 30 Nov 2013Funding: Hercules - Small and Medium size research infrastructure
- Education renewal project (OVP) 2008: From hearings to active think-tank. Pilots in the biological sciences.From1 Jan 2008 → 30 Jun 2010Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 21
- Polycomb group RING finger protein 5 influences several developmental signaling pathways during the in vitro differentiation of mouse embryonic stem cells(2020)
Authors: Ying Meng, Yang Liu, Eleni Dakou, Gustavo J Gutierrez, Luc Leyns
Pages: 232-242 - Loss of Emp2 compromises cardiogenic differentiation in mouse embryonic stem cells.(2019)
Authors: Yang Liu, Eleni Dakou, Ying Meng, Luc Leyns
Pages: 173-178 - Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia: a triosephosphate isomerase gene-targeted analysis(2018)
Authors: Luc Leyns
- Towards a New Paradigm in Nano-Genotoxicology(2016)
Authors: Laetitia Gonzalez, Enrico Cundari, Luc Leyns, Micheline Volders
Pages: 23-29 - Morphological observation of embryoid bodies completes the in vitro evaluation of nanomaterial embryotoxicity in the embryonic stem cell test (EST)(2015)
Authors: Sara Corradi, Eleni Dakou, Ajay Yadav, Leen C. J. Thomassen, Micheline Kirsch-Volders, Luc Leyns
Pages: 1587-1596 - Causes of genome instability: the effect of low dose chemical exposures in modern society(2015)
Authors: Sabine A. S. Langie, Gudrun Koppen, Daniel Desaulniers, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Amaya Azqueta, William H. Bisson, Dustin Brown, Gunnar Brunborg, et al.
Pages: S61-S88 - Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead(2015)
Authors: William H. Goodson III, Leroy Lowe, David O. Carpenter, Michael Gilbertson, Abdul Manaf Ali, Adela Lopez de Cerain Salsamendi, Ahmed Lasfar, Amancio Carnero, Amaya Azqueta, Amedeo Amedei, et al.
Pages: S254-S296 - Amorphous silica nanoparticles alter microtubule dynamics and cell migration(2015)
Authors: Laetitia Gonzalez, M De Santis Puzzonia, R. Ricci, F. Aureli, G. Guarguaglini, F. Cubadda, Luc Leyns, E. Cundari, Micheline Volders
Pages: 729-736 - Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on the in vitro genotoxic response to amorphous monodisperse silica nanoparticles of varying sizes(2014)
Authors: Laetitia Gonzalez, M. Lukamowicz-Rajska, Leen Thomassen, C.e.a. Kirschhock, Luc Leyns, Dominique Lison, Johan A. Martens, Azddine Elhajouji, Micheline Volders
Pages: 876-884 - Whole-mount in situ hybridization (WISH) optimized for gene expression analysis in mouse embryos and embryoid bodies(2014)
Authors: Eleni Dakou, Nele Vanbekbergen, Sara Corradi, Caroline Kemp, Erik Willems, Luc Leyns
Pages: 27-40