Researcher
Luc Leybaert
- Disciplines:Inflammation, Cell death, Cell therapy
Affiliations
- Department of Basic and Applied Medical Sciences (Department)
Member
From1 Oct 2018 → Today - Department of Basic Medical Sciences (Department)
Member
From1 Oct 2008 → 30 Sep 2018 - Department of General physiology and human physiology and pathophysiology (Department)
Member
From1 Jan 1993 → 30 Sep 2008
Projects
1 - 10 of 37
- Impact of peripheral virus infection on the central nervous systemFrom1 Jan 2023 → TodayFunding: BOF - projects
- CONNEXIN-43 HEMICHANNELS AS PRO-ARRHYTHMIC MEDIATORS IN CARDIAC HYPERTROPHY AND HEART FAILUREFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Cofunding core facility - Ghent Light Microscopy (GLiM)From1 Jul 2022 → TodayFunding: BOF - research organisations
- White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Long-term live cell imaging of intracellular signals and cell death.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Blood-brain barrier disturbances in response to ionizing radiation: role of connexin/calcium bystander signalingFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Controlled delivery of connexin43 mimetic peptide by nanocontainers for therapy of systemic inflammationFrom1 Oct 2018 → 31 Jul 2023Funding: BOF - Doctoral projects
- Combined single-channel electrophysiology and fluorescence microscopy for fundamental studies of ion channel functionFrom1 Jun 2018 → 31 May 2020Funding: BOF - Other initiatives
- Basic investigations on the role of connexin hemichannels as an arrhythmogenic substrate in ventricular arrhythmiaFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 195
- RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes(2021)
Authors: Alessio Lissoni, Tânia Martins-Marques, Nan Wang, Geert Bultynck, Rainer Schulz, Katja Witschas, Henrique Girao, Luc Leybaert
Pages: 123 - 136 - Christian Giaume (November 1951–July 2019)(2020)Volume: 68
Authors: Arantxa Tabernero, Annette Koulakoff, Lisa Roux, Laurent Venance, Luc Leybaert, Juan C. Sáez, Christian C. Naus
Pages: 1321 - 1328 - Gap19, a Cx43 hemichannel inhibitor, acts as a gating modifier that decreases main state opening while increasing substate gating(2020)
Authors: Alessio Lissoni, Nan Wang, Timur Nezlobinskii, Maarten De Smet, Alexander Panfilov, Nele Vandersickel, Luc Leybaert, Katja Witschas
- Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells(2020)
Authors: Delphine Hoorelbeke, Elke Decrock, Maarten De Smet, Marijke De Bock, Benedicte Descamps, Valérie Van Haver, Tinneke Delvaeye, Dmitri Krysko, Christian Vanhove, Geert Bultynck, et al.
- Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage(2020)
Authors: Raghda Ramadan, Els Vromans, Dornatien Chuo Anang, Ines Goetschalckx, Delphine Hoorelbeke, Elke Decrock, Sarah Baatout, Luc Leybaert, An Aerts
- Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model(2020)
Authors: Minerva Ferrer Buitrago, Laurentijn Tilleman, Vanessa Thys, A Hachem, Filip Van Nieuwerburgh, Dieter Deforce, Luc Leybaert, J. Parrington
Pages: 801 - 815 - Vitrification negatively affects the Ca2+-releasing and activation potential of mouse oocytes, but vitrified oocytes are potentially useful for diagnostic purposes(2020)
Authors: Davina Bonte, Vanessa Thys, Petra De Sutter, Annekatrien Boel, Luc Leybaert, Björn Heindryckx
Pages: 13 - 25 - Astrocytic Connexin43 channels as candidate targets in epilepsy treatment(2020)
Authors: Laura Walrave, Mathieu Vinken, Luc Leybaert, Ilse Smolders
- Single and fractionated ionizing radiation induce alterations in endothelial connexin expression and channel function(2019)
Authors: Raghda Ramadan, Els Vromans, Dornatien Chuo Anang, Elke Decrock, Mohamed Mysara, Pieter Monsieurs, Sarah Baatout, Luc Leybaert, An Aerts
- Risico op cardiovasculaire aandoeningen bij radiotherapie in de thoraxregio : de rol van een dysfunctioneel endotheel(2019)
Authors: Raghda Ramadan, Sarah Baatout, Luc Leybaert, An Aerts
Pages: 20 - 26
Patents
1 - 3 of 3