Researcher
Luc Bouwens
- Research Expertise:
- In vitro and in vivo models to induce islet regeneration or islet cell neogenesis and in which the effect of soluble growth factors, hormones, cytokines or pharmacological substances can be studied
- Regenerative medicine for diabetes
- Keywords:Medicine, General and logistic services
- Disciplines:Cell therapy, Metabolic diseases, Cell death, Tissue engineering, Gastro-enterology, Stem cell biology, Histology
- Users of research expertise:
- In vitro and in vivo models to induce islet regeneration or islet cell neogenesis and in which the effect of soluble growth factors, hormones, cytokines or pharmacological substances can be studied
- Regenerative medicine for diabetes
Affiliations
- Cell Differentiation (Research group)
Responsible
From1 Oct 2002 → Today - Vriendenkring VUB (Office)
Member
From1 Oct 2022 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Oct 2019 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → 30 Sep 2022 - Basic (bio-) Medical Sciences (Department)
Responsible
From1 Jan 2014 → 20 Oct 2022 - Cell Differentiation (Research group)
Member
From1 Jun 2002 → 1 Jun 2011 - Pathological Anatomy (Department)
Member
From1 Feb 1993 → 31 Dec 2013 - Cell Biology and Histology (Department)
Member
From1 Oct 1987 → 31 Jan 1993
Projects
1 - 9 of 9
- BRIDGE: Diatype : Personalized medicine in diabetes: towards an etiology-based diagnosis and better patient careFrom1 Jan 2018 → 31 Mar 2022Funding: Brussels Capital Region
- Pancreatic acinar cell reprogramming for beta cell regenerationFrom1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- SRP (Groeiers): Regenerative therapy in diabetesFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - Concerted Research Project from 1994
- Tracing and regulation of delta-to-beta cell conversionFrom1 Oct 2012 → 30 Dec 2019Funding: FWO fellowships
- Stimulation of beta cell neogenesis by EGF and CNTFFrom1 Oct 2010 → 30 Sep 2014Funding: FWO fellowships
- Stimulation of beta-cell progenitors in diabetic pancreasFrom1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- The role of Geminin in pancreas developmentFrom1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Multifoon confocale laser scanning microscoop voor imaging core faciliteit ter ondersteuning van onderzoek van de life sciences campus Jette en campus etterbeek -VUB.From1 Dec 2008 → 30 Nov 2013Funding: Hercules - Small and Medium size research infrastructure
- BetaImage: Use of innovative strategies for beta-cell imaging in diabetes mellitusFrom1 Oct 2008 → 31 Mar 2013Funding: Health
Publications
1 - 10 of 63
- Resolution of Acinar Dedifferentiation Regulates Tissue Remodeling in Pancreatic Injury and Cancer Initiation(2024)
Authors: Jonathan Baldan, Juan Camacho-Roda, Marta Ballester, Kristina Høj, Anita Kurilla, H Carlo Maurer, Sebastian Arcila-Barrera, Xinyi Lin, Zhaolong Pan, Joana Leitão Castro, et al.
Pages: 718-732.e18 - Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation(2022)
Authors: Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Jonathan Bastos, Monica Vara-Perez, Leen Ali, Myrthe Mampay, Lauren Deneyer, et al.
Pages: 2085-2102 - Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease(2022)
Authors: Sandrina Martens, Katarina Coolens, Mathias Van Bulck, Tatjana Arsenijevic, Joan Casamitjana, Angel Fernandez Ruiz, Abdessamad El Kaoutari, Jaime Martinez de Villareal, Hediel Madhloum, Farzad Esni, et al.
Pages: 2030-2042 - In vitro comparison of various antioxidants and flavonoids from Rooibos as beta cell protectants against lipotoxicity and oxidative stress-induced cell death(2022)
Authors: Céline Moens, Christo J. F. Muller, Luc Bouwens
- Rooibos phytochemicals as beta cell protectants(2022)
Authors: Céline Moens, Luc Bouwens
Number of pages: 173 - Transcutaneous Vagal Nerve Stimulation Alone or in Combination With Radiotherapy Stimulates Lung Tumor Infiltrating Lymphocytes But Fails to Suppress Tumor Growth(2021)
Authors: Eva Reijmen, Sven De Mey, Helena Van Damme, Kirsten De Ridder, Thierry Gevaert, Emmy De Blay, Luc Bouwens, Christine Collen, Lore Decoster, Marijke De Couck, et al.
- MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions(2021)
Authors: Elyne Backx, Elke Wauters, Mathias Van Bulck, Ellis Michiels, Y Heremans, Diedert L De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens, Patrick Jacquemin, et al.
Pages: 2601-2615 - MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions(2021)
Authors: Elyne Backx, Elke Wauters, Jonathan Baldan, Mathias Van Bulck, Ellis Michiels, Yves Heremans, Diedert L De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens, et al.
Pages: 2601-2615 - Fractionated Radiation Severely Reduces the Number of CD8+ T Cells and Mature Antigen Presenting Cells Within Lung Tumors(2021)
Authors: Eva Reijmen, Sven De Mey, Wout De Mey, Thierry Gevaert, Kirsten De Ridder, Hanne Locy, Sandrina Martens, Emmy De Blay, Luc Bouwens, Pieterjan Debie, et al.
Pages: 272-283 - Dynamic regulation of expression of KRAS and its effectors determines the ability to initiate tumorigenesis in pancreatic acinar cells(2021)
Authors: Mohamad Nabil Assi, Younes Achouri, Axelle Loriot, Nicolas Dauguet, Hajar Dahou, Jonathan Baldan, Maxime Libert, Jean S Fain, Carmen Guerra, Luc Bouwens, et al.
Pages: 2679-2689
Patents
1 - 3 of 3
- Biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells (Inventor)
- A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells (Inventor)
- A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells (Inventor)