Researcher
Linos Vandekerckhove
- Keywords:Long-non-coding, RNA, Interactome, HIV, HIV Cure, HIV reservoir, HIV animal models
- Disciplines:Virology, Transcription and translation, Cellular interactions and extracellular matrix
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2010 → 30 Sep 2018 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Oct 2008 → 30 Sep 2018
Projects
21 - 30 of 37
- Hybrid CAR – improving cellular therapies for infectious diseasesFrom1 Sep 2020 → 31 Aug 2021Funding: IOF - technology concept exploration
- Fonds A.B.: Blood and genome analyzes in the context of the Covid19-pandemicFrom1 Jul 2020 → 31 Dec 2021Funding: Foundations, funds and other with scientific goal
- COVID-Trace: from tracking virus-host interactions at the single-cell level to tracing cellular markers for clinical patient stratification.From22 May 2020 → 31 May 2021Funding: FWO Special Call for Covid-19 research projects
- Covid-Track: applying quantitative virology and single-cell genomics to unravel the virus-host interactions leading to severe immunopathologies in COVID-19 patientsFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Paving the way for a multidimensional therapeutic cure approach in patients treated during acute HIV seroconversionFrom1 Jan 2020 → 31 Aug 2023Funding: Foundations, funds and other with scientific goal
- HIV-1 integration as a driver of clonal expansion and HIV-1 transcription during antiretroviral therapyFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Strategies against persistent HIV-1 reservoirsFrom1 Jan 2020 → 31 Dec 2023Funding: FWO Strategic Basic Research (SBO)
- Use of bispecific AcTakines to boost innate and adaptive immune responses after acute HIV-1 infectionFrom15 Nov 2019 → 13 Jan 2024Funding: BOF - doctoral mandates
- Long non-coding RNAs in HIV latency: a new approach for improved latency reversal in shock-and-kill cure strategies.From1 Jan 2019 → 31 Mar 2023Funding: FWO Strategic Basic Research Grant
- Transferred Immunity by Gene Editing of Antigen Receptors (TIGEAR)From1 Jan 2019 → 31 Mar 2021Funding: IOF - technology concept exploration
Publications
1 - 10 of 132
- The Rainbow 5-plex digital PCR assay improves quantification of the viral reservoir resulting in a better understanding of the HIV-1 proviral landscape(2023)
Authors: Mareva Delporte, Laurens Lambrechts, Marion Pardons, Sofie De Braekeleer, Evy Blomme, Sofie Rutsaert, Wim Trypsteen, Linos Vandekerckhove
Pages: 77 - 77 - Unraveling ongoing inflammation after early ART by in-depth analysis of lymph nodes(2023)
Authors: Jozefien De Clercq, Kathleen Busman-Sahay, Laurens Lambrechts, Sofie Rutsaert, Sol Taylor-Brill, Stephen Bondoc, Marie-Angélique De Scheerder, Jacob Estes, Sarah Gerlo, Linos Vandekerckhove
Number of pages: 1 - No significant association between 25-OH vitamin D status and SARS-VoV-2 antibody response after COVID-19 vaccination in nursing home residents and staff(2023)
Authors: Eline Meyers, Hanne Vercruysse, Steven Callens, Elizaveta Padalko, Stefan Heytens, Linos Vandekerckhove, Piet Cools, Wojciech Witkowski
- Efficacy, durability, and tolerability of bictegravir/emtricitabine/tenofovir alafenamide for the treatment of HIV in a real‐world setting in Belgium(2023)
Authors: Rakan Nasreddine, Eric Florence, Jean Cyr Yombi, Sophie Henrard, Gilles Darcis, Jens Van Praet, Linos Vandekerckhove, Sabine D. Allard, Rémy Demeester, Peter Messiaen, et al.
Pages: 914 - 924 - Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size(2023)
Authors: Marc J. T. Blaauw, Jessica Cristina dos Santos, Nadira Vadaq, Wim Trypsteen, Wouter van der Heijden, Albert Groenendijk, Zhenhua Zhang, Yang Li, Quirijn de Mast, Mihai G. Netea, et al.
- Linking inducible HIV-1 reservoir to rebound after treatment interruption(2023)
Authors: Laurens Lambrechts, Ytse Noppe, Marion Pardons, Basiel Cole, Sofie Rutsaert, Stéphane De Wit, Guido Vanham, Eric Florence, Linos Vandekerckhove
Pages: 77 - 78 - Influence of UGT1A1 and SLC22A6 polymorphisms on the population pharmacokinetics and pharmacodynamics of raltegravir in HIV-infected adults : a NEAT001/ANRS143 sub-study(2023)
Authors: Rohan Gurjar, Laura Dickinson, Daniel Carr, Wolfgang Stohr, Stefano Bonora, Andrew Owen, Antonio D'Avolio, Adam Cursley, Nathalie De Castro, Gerd Fatkenheuer, et al.
Pages: 14 - 20 - Sniffing out safety : canine detection and identification of SARS-CoV-2 infection from armpit sweat(2023)
Authors: Chris Callewaert, Maria Pezavant, Rony Vandaele, Bart Meeus, Ellen Vankrunkelsven, Phaedra Van Goethem, Alain Plumacker, Benoit Misset, Gilles Darcis, Sonia Piret, et al.
- Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir(2023)
Authors: Marion Pardons, Basiel Cole, Laurens Lambrechts, Willem van Snippenberg, Sofie Rutsaert, Ytse Noppe, Nele De Langhe, Annemieke Dhondt, Jerel Vega, Filmon Eyassu, et al.
- Rethinking IL-1 antagonism in respiratory viral infections : a role for IL-1 signaling in the development of antiviral T cell immunity(2023)
Authors: Bram Van Den Eeckhout, Marlies Ballegeer, Jozefien De Clercq, Elianne Burg, Xavier Saelens, Linos Vandekerckhove, Sarah Gerlo
Patents
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