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Researcher
Ling-Jie Gao
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From7 Nov 2011 → Today - Tracheal Transplantation (Lab)
Member
From1 Apr 2010 → 6 Nov 2011
Publications
1 - 10 of 17
- Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents(2023)
Authors: Ling-Jie Gao, Steven De Jonghe, Mark Waer, Piet Herdewyn
- Preparation and validation of cyclodextrin-based excipients for radioiodinated hypericin applied in a targeted cancer radiotherapy(2021)
Authors: Shuncong Wang, Ling-Jie Gao, Yicheng Ni
- Drug Discovery of Nucleos(t)ide Antiviral Agents: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Birthday(2021)
Authors: Weijie Gu, Ling-Jie Gao
- The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis inStaphylococcus aureusby Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI(2020)
Authors: Michiel Vanmeert, Ling-Jie Gao, Eveline-Marie Lammens, Piet Herdewyn, Eveline Lescrinier, Rob Lavigne, Joleen Masschelein
Pages: 10549 - 10556 - Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3-b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity(2019)
Authors: Sven Verdonck, Mathy Froeyen, Ling-Jie Gao, Piet Herdewyn, Steven De Jonghe
Pages: 5810 - 5831 - Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo(2018)
Authors: Ling-Jie Gao, Piet Herdewyn, Yuan Lin, Thierry Louat, Mark Waer
Pages: 6705 - 6723 - L-Aspartic and L-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluation(2016)
Authors: Ling-Jie Gao, Steven De Jonghe, Dirk Daelemans, Piet Herdewyn
Pages: 2142 - 6 - Synthesis of a Nucleobase-Modified ProTide Library(2016)
Authors: Ling-Jie Gao, Steven De Jonghe, Piet Herdewyn
Pages: 5816 - 5819 - Bifunctional aryloxyphosphoramidate prodrugs of 2 '-C-Me-uridine: synthesis and anti-HCV activity(2016)
Authors: Ling-Jie Gao, Steven De Jonghe, Piet Herdewyn
Pages: 8743 - 8757 - Synthesis and Structure-Activity Relationship Studies of 2-(1,3,4-Oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as Inhibitors of DRAK2(2014)
Authors: Piotr Leonczak, Ling-Jie Gao, Eveline Lescrinier, Jef Rozenski, Steven De Jonghe, Piet Herdewyn
Pages: 2587 - 2601
Patents
1 - 10 of 10
- Novel prodrugs of mizoribine (Inventor)
- Antiviral activity of bicyclic heterocycles (Inventor)
- Novel prodrugs of mizoribine (Inventor)
- Purine analogues and their use as immunosuppressive agents (Inventor)
- Antiviral activity of novel bicyclic heterocycles (Inventor)
- Thiazolopyrimidine modulators as immunosuppressive agents (Inventor)
- Antiviral activity of bicyclic heterocycles (Inventor)
- Novel antiviral and antitumoral compounds (Inventor)
- Thiazolopyrimidine modulators as immunosuppressive agents (Inventor)
- THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS (Inventor)